Pachytene

pachytene
the stage of prophase during meiosis I in which homologous chromosomes are paired; they are condensing and coiling
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
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Pachytene
[Gr. pachytes - thickness; Gr. tainia - ribbon]. The third stage in prophase 1 of meiosis in which there is further shortening and thickening of the bivalents.
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Pachytene
The term proposed by von Winiwarter (1900), originally as an adjective, to describe the nuclei at a particular stage of prophase 1 of meiosis when homologous chromosomes are associated throughout their length. (Gk.
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3. Pachytene
Synapsis is now complete.
Recombination nodules appear (at least in some organisms, including humans). They are named for the idea that they represent points where DNA recombination is occurring.
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The pachytene stage heralds crossing over. Nonsister chromatids of homologous chromosomes exchange segments of genetic information.
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In late pachytene there are twice as many nodules as in early diplotene, but they have different appearances, making it uncertain as to whether early nodules mature into late ones or late nodules arise de novo.
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The expression of mouse XPF in pachytene spermatocytes corroborates other indications that XPF has an additional role in genetic recombination during meiosis.
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Pachytene: starts right after the synaptonemal complex is fully formed (when synapsis ends), crossing over occurs.
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(1) Four homologous chromatids in a bundle in the first meiotic prophase and metaphase. The meiotic configuration of four chromatids first seen in pachytene. There is one tetrad per pair (bivalent) of homologous chromosomes.
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