Oligonucleotide

Oligonucleotide microchips have been tested as diagnostics of genetic hybridization diseases. Several methods have been evaluated for the preparation of hybridization probes.
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Oligonucleotide
A short sequence of polynucleotide. Oligonucleotides with a defined sequence can synthesized in vitro for use for a variety of techniques, including PCR, DNA sequence analysis, hybridization, and site-directed mutagenesis.
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Oligonucleotide, short sequence of single-stranded DNA or RNA. Oligos are often used as probes for detecting complementary DNA or RNA because they bind readily to their complements.
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Oligonucleotide
A short fragment of single-stranded DNA typically 5 to 50 nucleotides.
Related Terms: Deoxyribonucleic acid (DNA) ...
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Oligonucleotide microarrays, including comparative genomic hybridization and single nucleotide polymorphism arrays, ...
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oligonucleotide - piece of single-stranded nucleic acid, short stretch of nucleotides.
oogamy - a specialized form of heterogamy, which involves the production of large, relatively immotile eggs by one mating type and small, motile sperm by the other.
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OLIGONUCLEOTIDE - See OLIGODEOXYRIBONUCLEOTIDE.
ONCOGENE - One of a number of genes believed to be associated with the malignant transformation of cells; ...
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Oligonucleotide. A DNA polymer composed of only a few nucleotides. (See Nucleotide.) ...
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Oligonucleotide: See Oligodeoxyribonucleotide.
Oncogene: A gene in a tumor virus or in cancerous cells which, when transferred into other cells, ...
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A short oligonucleotide complementary to target DNA and acts as the leader for DNA extension. Also refers to short oligonucleotide used to primer reverse transcription of RNA to DNA in reverse transcription reactions. See PCR Glossary.
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A pair of oligonucleotides complementary to conserved regions flanking a VNTR region is made. The size of PCR products can be analyzed directly.
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Primer: A small oligonucleotide (anywhere from 6 to 50 nt long) used to prime DNA synthesis.
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A short, double-stranded oligonucleotide containing a restriction endonuclease recognition site, which is ligated to the ends of a DNA fragment. Liposomes. Membrane-bound vesicles constructed in the laboratory to transport biological molecules.
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In practice, when synthesising an oligonucleotide primer or probe based on this information a mixture of all the possible sequences is made, and referred to as a degenerate oligonucleotide.
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oligonucleotide A few (usually less than 50) nucleotides joined by phosphodiester bonds. oligopeptide A few amino acids (usually less than 50) joined by peptide bonds.
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Obestatin Oceanic zone Okazaki fragment OKT3[More] Olfaction, the sense of smell OligonucleotideA short polymer of, for example, 20 or so deoxyribonucleotides or ribonucleotides; thus a fragment of DNA or RNA.
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Khorana was also the first to synthesize oligonucleotides , that is, strings of nucleotides. These custom designed pieces of artificial genes are widely used in biology labs for sequencing, cloning and engineering new plants and animals.Dr.
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These primers are short oligonucleotides chosen by the experimenter and added to the DNA mixture at the beginning. They flank the region to be amplified. One binds to the + strand and the other binds to the - strand.
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Two oligonucleotide primers (oligos) are constructed to flank a region of interest. One oligo will be complementary to a region on one strand of DNA, and the other oligo will be complementary to a region downstream on the homologous strand.
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A right-handed double-helical conformation of DNA normally seen in solution described by Watson and Crick. A second DNA conformation (A form) is seen in unhydrated DNA (fibres or crystals of oligonucleotides).
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VNTR -- variable number tandem repeats; any gene whose alleles contain different numbers of tandemly repeated oligonucleotide sequences. Vector -- a self-replicating DNA molecule that transfers a DNA segment between host cells.
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