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Nucleoside


Nucleosides are produced as the second step in nucleic acid digestion, when nucleotidases break down nucleotides (such as the thymine nucleotide) into nucleosides (such as thymidine) and phosphate.
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A synthetic molecule that resembles a naturally occuring nucleoside, but that lacks a bond site needed to link it to an adjacent nucleotide.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
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Nucleosides are glycosylamines made by attaching a nucleobase to a ribose ring. Examples of these include cytidine, uridine, adenosine, guanosine, thymidine and inosine.
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Nucleoside
A sugar-base compound that is a nucleotide precursor. Nucleotides are nucleoside phosphates. A nitrogenous base linked to a sugar molecule.
Related Terms: Nucleotide ...
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Nucleoside analog
See analog.
Nucleotide
A nucleoside with a phosphate group attached.
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nucleosides - compound composed of a purine or pydimidine base linked to either a ribose or deoxyribose sugar. DNA and RNA are not polymers of nucleosides.
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Nucleoside analogs. Examples:
zidovudine (AZT)(Retrovir)
lamivudine (Epivir)
didanosine (Videx) ...
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nucleoside
(noo-klee-oh-side)
An organic molecule consisting of a nitrogenous base joined to a five-carbon sugar.
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NUCLEOSIDE - The composite sugar and purine or pyrimidine base which are present in nucleotides which are the basic building blocks of DNA and RNA. Compare with NUCLEOTIDE:
Nucleoside = Base + Sugar ...
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Nucleoside: A term refering to the combination of adenine, cytosine, guanine, or thymine with a ribose or 2-deoxyribose sugar moiety. A nucleoside is not phosphorylated.
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The nucleoside containing adenine as its base.
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5' or 3' end The nucleoside residues which form nucleic acids are joined by phosphodiester linkages between the 3' C atom of one ribose moiety and the 5' C atom of the next.
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Nucleoside. A building block of DNA and RNA, consisting of a nitrogenous base linked to a five carbon sugar. (See Nucleoside analog.) Nucleoside analog.
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adenosine diphosphate (ADP) A ribonucleoside 5'-diphosphate serving as phosphate group acceptor in the cell energy cycle. adenosine triphosphate (ATP) A ribonucleoside 5'-triphosphate functioning as a phosphate group donor in the cell energy cycle.
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For such chemical modifications to be of practical significance, it would be useful to be able to employ the corresponding 2'-modified nucleoside triphosphates in the polymerase-directed synthesis of DNA.
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Included in this group are the nucleoside analogs, chemicals that are similar to one of the bases (adenine, cytosine, guanine, and thymine) that comprise DNA, but sufficiently different enough to block viral DNA synthesis.
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Biochemical energy for translation is derived from nucleoside triphosphates at three steps. Charging of tRNA requires ATP to form an aminoacyl adenylate intermediate. Adenylate is later released as AMP.
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