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Nondisjunction


nondisjunction
the failure of chromosomes to separate properly during cell division
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
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Nondisjunction is the failure of chromosome pairs to separate properly during meiosis or mitosis. The result of this error is a cell with an imbalance of chromosomes.
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Nondisjunction
In biology, nondisjunction is the failure of a chromosome to split correctly during meiosis.
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Nondisjunction occurs when chromosomes fail to "disjoin" during meiosis or mitosis.
Meiosis
Metaphase I ...
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Nondisjunction
Chromosome pairs do not disjoin (separate) during cell division so that both chromosomes go to one daughter cell and none to the other. Nondisjunction causes errors in chromosome number (trisomy).
Cell division ...
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nondisjunction The failure of chromosomes to separate properly during cell division. The unequal segregation of chromosomes during meiosis.
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nondisjunction
[L. non, not + disjungere, to separate]
An accident of meiosis or mitosis, in which both members of a pair of homologous chromosomes or both sister chromatids fail to move apart properly.
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nondisjunction. Failure of a pair of homologous chromosomes to separate during meiosis, leading to one gamete with n + 1 chromosomes (see trisomy) and another gamete with n _ 1 chromosomes.
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Advanced maternal age -- women over age 34 (age 35 at delivery) at increased risk for nondisjunction trisomy in fetus. Alcoholism -- a chronic and progressive condition characterized by the inability to control the consumption of alcohol.
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On rare occasions, nondisjunction occurs during meiosis with the loss of one X chromosome. Animals with a single X are males and are able to fertilize the eggs of the hermaphrodites (with more success than they have themselves).
C.
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: Separation of homologous chromosomes during anaphase of mitotic or meiotic divisions (see also
nondisjunction
).
Disposable soma theory ...
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