Monoclonal

Monoclonal Antibodies
Humans (and mice) have the ability to make antibodies able to
recognize (by binding to) virtually any antigenic determinant (epitope)
to discriminate between even similar epitopes.
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Monoclonal antibody
Monoclonal antibodies (mAb) are antibodies that are identical because they were produced by one type of immune cell, all clones of a single parent cell.
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monoclonal antibody
(mon-oh-klone-ul)
A defensive protein produced by cells descended from a single cell; an antibody that is secreted by a clone of cells and, consequently, is specific for a single antigenic determinant.
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Monoclonal antibodies. Immunoglobulin molecules of single- epitope specificity that are secreted by a clone of B cells.
Monoculture. The agricultural practice of cultivating crops consisting of genetically similar organisms.
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Monoclonal antibodies took about 20 years from the time they first came on the scene to actually deliver us really wonderful, useful products- such as for treating autoimmune disease.
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Monoclonal Antibody: An antibody with very specific and often unique binding specificity which is secreted by a biologically cloned line of plasmacytoma cells in the absence of other related antibodies with different binding specificities.
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"Designed" monoclonal antibody therapy is already being employed in a number of diseases (including rheumatoid arthritis) and in some forms of cancer.
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(See monoclonal antibodies, polyclonal antibodies.) Anticodon. A nucleotide base triplet in a transfer RNA molecule that pairs with a complementary base triplet, or codon, in a messenger RNA molecule. See Codon, Messenger RNA, RNA. Antigen.
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Memorial Sloan-Kettering Cancer Center, New York
Pioneering work in the use of "monoclonal antibodies" to treat cancer. Novel ways to produce a variety of radionuclides to treat lymphoma, leukemia, and prostate cancer.
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Ci antibody staining using either monoclonal or polyclonal antibodies is localized primarily in the cytoplasm. Low levels of ci protein were detected when compared to the nuclei of en expressing cells (Fig 3) (Motzny, 1995).
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monoclonal antibodies Antibodies produced by a cloned hybridoma cell, which therefore are identical and directed against the same epitope of an antigen. monolayer A single layer of oriented lipid molecules or cells.
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To demonstrate the molecular basis of the specificity of anti-neoepitope antibodies, the Fv region of a monoclonal antibody specific for a neoepitope generated by the ADAMTS-4-mediated cleavage of aggrecan has been modelled and the binding of the ...
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More sophisticated techniques are now in development that can track protein products without mitigating their function, such as the addition of small sequences which will serve as binding motifs to monoclonal antibodies.
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