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Linkage disequilibrium


In population genetics, linkage disequilibrium is the non-random association of alleles at two or more loci, not necessarily on the same chromosome. It is not the same as linkage, which describes the association of two or more loci on a chromosome with limited...
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linkage disequilibrium ( ¦liŋkij dis′ēkwə′librēəm ) ( genetics ) The occurrence in a population of certain combinations of linked alleles in
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That is where linkage disequilibrium comes it: LD basically measures the ... linkage disequilibrium = population wide measure of interlocus allelic associations ...
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The extent and distribution of linkage disequilibrium(LD) in humans is a topic ... Second, linkage disequilibrium studies will be most effective in detecting ...
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Recent work has shown that linkage. disequilibrium can extend over much larger genomic ... a number of studies of linkage disequilibrium in the past ...
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Linkage disequilibrium occurs when genotypes at the two loci are not independent ... term linkage disequilibrium is ... Measuring linkage disequilibrium ...
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Sequence features in regions of weak and strong linkage disequilibrium ... Regions of high and low linkage disequilibrium (the top and bottom quartiles of ...
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Linkage disequilibrium (LD) mapping can precisely locate genes of small effect ... Abecasis GR, Cookson WO (2000) GOLD—graphical overview of linkage disequilibrium. ...
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To model linkage disequilibrium, MERLIN organizes markers into clusters. ... This file describes clusters of SNPs in linkage disequilibrium. ...
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Linkage Disequilibrium. If all polymorphisms were independent at ... Linkage disequilibrium makes tightly linked. variants strongly correlated producing cost ...
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Nonstandard abbreviations used: LD, linkage disequilibrium; LDU, LD unit; SNP, ... L, ε) predicting linkage disequilibrium among m markers in a physical map or ...
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Linkage disequilibrium (LD), defined as non-random association of alleles at two ... 5. Linkage disequilibrium in human and animal populations ...
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Linkage disequilibrium is an important tool both at the end stages of positional ... inference for linkage disequilibrium cannot rely ...
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... and the degree of linkage disequilibrium in the genome. We show that variation in linkage disequilibrium is ... Linkage disequilibrium is generally low within ...
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In other words, it occurs when linkage disequilibrium is at zero. ... The geneticist Linda Partridge explains the concepts of linkage equilibrium and disequilibrium. ...
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Linkage disequilibrium between two linked loci was studied for a finite ... A Genealogical Interpretation of Linkage Disequilibrium ...
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... allelic association (also referred to as linkage disequilibrium) studies are two ... Such a joint linkage and linkage disequilibrium mapping strategy has been ...
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... these parameter values: linkage equilibrium. D, the coefficient of disequilibrium. Adjust the initial allelic frequencies and the two-locus fitness values to ...
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