Inducer

inducer
a small molecule that induces transcription from an operon
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
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Inducer
A chemical or physical agent that turns on gene expression. Usually refers to an agent that alters repressor-operator interactions, often by decreasing DNA-binding.
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inducer gene - gene encoding the repressor protein of the lac operon; when lactose binds the repressor protein, the lac operon is induced.
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Inducer: A small molecule, such as IPTG, that triggers gene transcription by binding to a regulator protein, such as LacZ.
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inducere, to induce]
(1) The ability of one group of embryonic cells to influence the development of another.
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If an inducer, a molecule that initiates the gene expresssion, is present, then it binds to the repressor protein and deattaches from the operator. The RNA polymerase then can create the messenger RNA and allow the gene to be expressed.
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inducer A signal molecule that, when bound to a regulatory protein, produces an increase in the expression of a given gene. induction An increase in the expression of a gene in response to a change in the activity of a regulatory protein.
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Our results demonstrate that, in the presence of an inducer, the repressor's N-termini crosslink to the operator's outermost nucleotides.
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p53 is a potent inducer of apoptosis. Is it any wonder that mutations in the p53 gene, producing a defective protein, are so often found in cancer cells (that represent a lethal threat to the organism if permitted to live)?
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Intrinsic and extrinsic inducers
Apoptotic messages from outside the cell (called extrinsic inducers) will be described in the next section, on biochemical execution of apoptosis.
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Genes which code for enzymes necessary for the digestion of maltose are regulated by this mechanism. Maltose acts as the inducer, binding to an activator and then to mRNA. The activator bound to mRNA stimulates the binding of RNA polymerase.
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