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Histocompatibility


Histocompatibility molecules are glycoproteins expressed at the surface of almost all vertebrate cells.
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Because of the involvement of histocompatibility antigens in antigen presentation, some alleles of these loci are associated with resistance or susceptibility to particular diseases.
Proteins can serve as molecular markers for the genetic chromosome.
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Major histocompatibility complex
The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates containing many genes with important immune system roles.
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histocompatibility antigens - cell surface glycoproteins that differ from individual to individual; their recognition as foreign by a host organism is responsible for rejection of grafted foreign tissue.
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The histocompatibility Y-antigen, a protein found on the cell surfaces of male mammals.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
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major histocompatibility complex (MHC)
A large set of cell surface antigens encoded by a family of genes. Foreign MHC markers trigger T-cell responses that may lead to the rejection of transplanted tissues and organs.
Malpighian tubule ...
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major histocompatibility complex (MHC). Complex of genes coding for proteins inserted in the cell membrane; the proteins are the basis of self-nonself recognition by the immune system.
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: The major histocompatibility complex (
MHC
) of the mouse. It is the first MHC discovered in 1937 by Peter Gorer.
Hairpin loop ...
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BoLA Nomenclature Committee information source on the bovine major histocompatibility complex - its genes, proteins and polymorphism.
BRITE database of binary relations for computation and graph comparisons ...
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One case of this phenomenon occurs at loci at the major histocompatibility complex (MHC) wherein some human alleles are much more closely related to some chimpanzee alleles than they are to other human alleles (Fig. 7).
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The fragments are then presented on the cell surface in the complex with class I histocompatibility molecules.
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Success of organ transplants and skin grafts requires a matching of histocompatibility antigens that occur on all cells in the body.
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