Heterozygosity

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Definition of heterozygosity :
A measure of the genetic variation in a population; with respect to one locus, stated as the frequency of heterozygotes for that locus.
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Heterozygosity
The presence of different alleles of a gene at one or more loci. Cf. heterozygote
Related Terms: Allele ...
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Heterozygosity: The presence of different alleles at one or more loci on homologous chromosomes.
Histones: Highly basic proteins which associate with the chromosomal DNA to package it into a compact, higher order structure.
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Loss Of Heterozygosity (LOH)
Because tumor suppressor genes are recessive, cells that contain one normal and one mutated gene — that is, are heterozygous — still behave normally.
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Loss of heterozygosity: loss of one allele, either by a deletion or recombination event, in organisms which previously had two.
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By effect on function ...
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The effect of heterozygosity depends on the protein product coded for by the gene in question. In some cases a mixture of normal and abnormal proteins is produced. In other cases, the abnormal allele may produce no protein at all.
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An experimental strategy for detecting heterozygosity in genomic DNA has been developed based on a preferential binding of Escherichia coli MutS protein to DNA molecules containing mismatched bases.
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The rate of mutation determines the level of heterozygosity at a locus according to the neutral theory. Heterozygosity is simply the proportion of the population that is heterozygous.
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heterozygosity
for the dominant allele result in the same genotype in complete dominance (if red is dominant over white, the petals of a flower heterozygous for red and white would be red).
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Offspring of parents that differ in only one genetic characteristic. Usually implies heterozygosity at a single locus under study.
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