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Heteroplasmy


Heteroplasmy is the presence of a mixture of more than one type of an organellar genome or plastid DNA) within a cell or individual. Since every eukaryotic cell contains many hundreds of mitochondria with hundreds of copies of mtDNA, it is possible and indeed very frequent for mutations to affect only some of the copies, while the remaining ones are...
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Aspects of the topic heteroplasmy are discussed in the following places at Britannica. Assorted References mitochondrial DNA mutations ( in human genetic disease: Mitochondrial DNA mutations ) ...triphosphate (ATP). Severity and even penetrance can vary widely for disorders resulting from mutations in the mitochondrial DNA, generally believed to reflect the...
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Introduction of the mitochondrial Eve story. Is the Mitochondrial Clock speed ... This confirms heteroplasmy in the Tsar's lineage, and is powerful evidence ...
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Heteroplasmy of the Human mtDNA Control Region Remains Const... On the basis of our results, heteroplasmy in the control region of mtDNA seems ...
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... equation allows confirmation of the heteroplasmy level in mtDNA. ... Measurement of levels of heteroplasmy in plasmid DNA samples with known mutant loads. ...
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(VNTRs), heteroplasmy, and sequence variation of the mitochondrial control region ... in Lunt et al. 1998), and heteroplasmy (intra-indi ...
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This heteroplasmy allows the generation of multi-locus recombinants, as ... Key Words: mitochondrial genomicsheteroplasmy • leakage • gynodioecy • Silene ...
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This type of heteroplasmy resembles one observed in patients with mitochondrial ... Mitochondrial DNA heteroplasmy in Drosophila mauritiana. ...
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We examine the utility of mtDNA heteroplasmy in assessing genetic damage due to ... Site heteroplasmy was qualified in a 400 bp portion of the cytochrome b gene in ...
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Heteroplasmy was determined, as described below, using PCR primers encompassing ... Determination of heteroplasmy. The percentage heteroplasmy of the A3243G, ...
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A Case of Chloroplast Heteroplasmy in Kiwifruit (Actinidia deliciosa) That Is ... Mitochondrial DNA Heteroplasmy in Wheat, Aegilops and Their Nucleus-Cytoplasm ...
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The level of heteroplasmy (meaning the presence of both normal and rearranged ... NARP is typically associated with 70-90% heteroplasmy of mutant mitochondria. ...
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An official journal of the Genetics Society, Heredity publishes high-quality articles describing original research and theoretical insights in all areas of ...
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PLoS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. ... Therefore, heteroplasmy is considered as a transitional and ...
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The interpretation of heteroplasmy can further be confounded by the widespread ... In some cases, if the heteroplasmy is inherited, it substantially increases the ...
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This study strongly supports the thesis that heteroplasmy ... levels of heteroplasmy were observed even among roots from the ... Generally, heteroplasmy com ...
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