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Gyrase


Gyrase: An enzymatic activity responsible for maintaining supercoiling in DNA.
H
Hairpin: A helical (duplex) region formed by base pairing between adjacent (inverted) complementary sequences within a single strand of RNA or DNA.
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DNA gyrase
A topoisomerase that removes supercoils from DNA by first producing double-strand breaks and then sealing them.
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DNA gyrase: catalyzes the negative supercoiling of prokaryotic DNA
Glutamate decarboxylase: synthesizes the neurotransmitter GABA in the brain
Glutathione peroxidase: protects cells by converting hydrogen peroxide to water ...
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Some bacteria do this by modifying their DNA gyrase.
Others, e.g., Mycobacterium tuberculosis, develop quinolone resistance by synthesizing a protein that resembles a short length of DNA.
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