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Gene product


The biochemical material, either RNA or protein, resulting from expression of a gene. The amount of gene product is used to measure how active a gene is; abnormal amounts can be correlated with disease-causing alleles.
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Name of Gene Product: hemoglobin, beta
Alternate Name of Gene Product: beta globin
Locus: 11p15.5 - The HBB gene is found in region 15.5 on the short (p) arm of human chromosome 11.
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All these gene products are used within the mitochondrion, but the mitochondrion also needs proteins encoded by nuclear genes.
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A gene product (usually protein) that positively regulates transcription. Activators may either increase binding of RNA polymerase to the promoter (closed complex formation) or stimulate RNA polymerase to begin transcription (open complex formation).
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The synthesis of gene products is driven by kinases which in turn activate transcription factors that mediate gene expression.
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The scarecrow-like gene products or transcription factors are involved in very early cellular differentiation and development.
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DNA probe -- any biochemical used to identify or isolate a gene, a gene product, or a protein.
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gene expression The production of a biologically active gene product, either constitutive or regulated. gene splicing The enzymatic attachment of one exon to another.
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Today, 12 functional chicken cystatin relatives are known in humans, but a few evolutionarily related gene products still remain to be characterized.
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Two additional classes of segmentation genes are expressed after the gap gene products. The pair-rule genes are expressed in striped patterns of seven bands perpendicular to the anterior-posterior axis (see the example, even-skipped).
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Now the term allele is used for two or more alternative forms of a gene resulting in different gene products and thus different phenotypes. In a haploid set of chromosomes there is only one allele at its specific locus.
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FUSION PROTEIN - A product of recombinant DNA in which the foreign gene product is juxtaposed ("fused") to either the carboxyl-terminal or amino-terminal portion of a polypeptide encoded by the vector itself.
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Some organisms have evolved mechanisms of gene amplification to provide gene products needed in large quantities. These mechanisms include:
Elaboration of small "extrachromosomal" units that replicate to high copy number (rDNA); ...
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exon Part of the mRNA as transcribed from the DNA that contains a portion of the information necessary for final gene product.
exopod, exopodite. Lateral branch of a biramous crustacean appendage.
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about 1000 chromatids; produced by DNA replication without mitosis. When viewed under a microscope, the many chromatids look like a giant chromosome. The large number of chromatids allows the cell to produce more mRNA and therefore more gene product ...
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of transcriptional regulation allows a rich substrate for morphological diversity, since variations in the level, pattern, or timing of gene expression, may provide more variation for natural selection to act upon, than changes in the gene product ...
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These are types of mutations. Since DNA is information, and information typically has a beginning point, an inversion would produce an inactive or altered protein. Likewise deletion or duplication will alter the gene product.
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