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Frame-shift


frame-shift mutation A mutation caused by the insertion or deletion of nucleotides (less than three or a number not a multiple of three) resulting in the improper grouping into codons.
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Frame-shift: A change from one reading frame to another.
Frameshift Mutation: A mutation (deletion or insertion, never a simple substitution) of one or more nucleotides but never a multiple of 3 nucleotides, ...
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Smith-Waterman
Frame-Shift Tolerant
User programmable similarity matrix; and affine gap scoring. Searches 3 nt frames vs. aa target simultaneously with user set frame shift and gap penalties.
100 Million S-W matrix
cells/sec ...
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inter- among, between intercalating mutagen A mutagen that inserts itself between two successive bases in a nucleic acid causing a frame-shift mutation. intercalation Insertion between two stacked aromatic or planar rings.
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BACK MUTATION - Reverse the effect of a point or frame-shift mutation that had altered a gene; thus it restores the wild-type phenotype (see REVERTANT).
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Genes for some mRNAs should be difficult to recognize from nucleotide sequences due to extensive editing of their transcripts.
The paramyxovirus frame-shifting insertion illustrates another way in which one gene can give rise to more than one ...
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Frame-shift mutations occur when the reading frame of the gene is shifted by addition or deletion of one or more bases. With the exception of mitochondria, all organisms use the same genetic code.
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