Feedback inhibition

feedback inhibition
inhibition of an enzyme by a product of the pathway catalyzed by the enzyme
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
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feedback inhibition
A method of metabolic control in which the end-product of a metabolic pathway acts as an inhibitor of an enzyme within that pathway.
feedback systems ...
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Feedback Inhibition
Negative feedback inhibition is like a thermostat. When it is cold, the thermostat turns on a heater which produces heat. Heat causes the thermostat to turn off the heater.
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Feedback Inhibition
If the product of a series of enzymatic reactions, e.g., an amino acid, begins to accumulate within the cell, it may specifically inhibit the action of the first enzyme involved in its synthesis (red bar).
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For other uses, including audio feedback, see Feedback (disambiguation)
Feedback is (generally) information about actions.
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feedback inhibition Inhibition of an allosteric enzyme at the beginning of a metabolic sequence by the end product of the sequence. fermentation Energy-yielding anaerobic breakdown of a nutrient molecule, such as glucose, without net oxidation.
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Figure 3: Common feedback inhibition mechanisms, (1) The basic feedback inhibition mechanism, where the product (P) inhibits the committed step (A->B). (2) Sequential feedback inhibition.
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Binding of an allosteric effector changes the shape of the enzyme, inactivating it while the effector is still bound. Such a mechanism is commonly employed in feedback inhibition.
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