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Exons


Exons are the regions of DNA within a gene that are not spliced out and which are retained in the final mRNA molecule.
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Exons are the regions of DNA within a gene that are not spliced out from the transcribed RNA and are retained in the final messenger RNA (mRNA) molecule. Exons of many eukaryotic genes is interrupted by segments of non-coding DNA (introns).
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Exons and "The Curly Shuffle"
Introduction to polymerase chain reaction (PCR)
The universe of exons ...
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exons whose sequence encodes the polypeptide;
introns that will be removed from the mRNA before it is translated [Discussion];
a transcription start site
a promoter ...
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The inclusion or exclusion of different exons to form different mRNA transcripts. (See RNA.) Amino acid. Any of 20 basic building blocks of proteins-- composed of a free amino (NH2) end, a free carboxyl (COOH) end, and a side group (R).
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Exons -- portion of a gene included in the transcript of a gene and survives processing of the RNA in the cell nucleus to become part of a spliced messenger of a structural RNA in the cell cytoplasm; ...
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Developed improved systems for recognition of exons, splice junctions, promoter elements and other features of biological importance, ...
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Eukaryotic DNA contains both exons (coding sequences) and introns (intervening sequences). In eukaryotic cells this DNA is used as a template for the production of mRNA, which must then undergo mRNA splicing.
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RNase protection assay: This is a sensitive method to determine (1) the amount of a specific mRNA present in a complex mixture of mRNA and/or (2) the sizes of exons which comprise the mRNA of interest.
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To analyze splicing in vitro, a plasmid vector was prepared that contained the intron and parts of the exons downstream of a phage RNA polymerase promoter.
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Introns are cut out of the message and the exons are spliced together before the mRNA leaves the nucleus. There are several examples of identical messages being processed by different methods, often turning introns into exons and vice-versa.
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Eukaryotic cells splice the transcripts of a gene, by keeping the exons and removing the introns. So, the DNA strand needs to be in an exon to be expressed.
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The hypothesis put forward by Walter Gilbert that exons code for functional units of a protein and that evolution of new genes has proceeded by recombination or exclusion of exons.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
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Mature transcript of RNA splicing which removes introns and joins exons in the primary transcript. mRNA usually has a 5' UTR, 3' UTR and polyA.
Related
3' UTR 5' UTR Mature transcript Primary transcript Splicing cis-splicing polyA trans-splicing ...
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any non-intron section of the coding sequence of a gene; together, the exons constitute the mRNA and are translated into protein
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row
...
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The remaining portions of mRNA are called exons. They are spliced together to form a mature mRNA transcript.
The Nucleus
DNA is located in an organelle called the nucleus.
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intron An intervening or noncoding segment of a gene; introns separate exons.
introvert A tubular, eversible extension of the head, bearing the mouth at its tip.
invagination An infolding of a layer of tissue to form a sac-like structure.
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In alternative splicing, the same pre-mRNA molecule, which consists of introns and exons, is spliced in different ways to produce mature mRNAs of different lengths and different functionality.
altruistic behavior
(al-troo-is-tik) ...
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A process by which introns are removed from primary See RNA transcripts leaving only exons that encode the amino acid sequence of a protein.
Related Terms: Intron ...
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exon - segment of DNA sequence in a gene that will be transcribed in the nucleus, spliced to other exons, and transported to the cytoplasm as a part of the mature mRNA; see also intron.
Back to the Top ...
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Each exon codes for a specific portion of the complete protein. In some species (including humans), a gene's exons are separated by long regions of DNA (called introns or sometimes "junk DNA") that have no apparent function.
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their function nor of the genetics of the organism. This can be accomplished because different gene features, such as exons, introns, promoters, polyadenylation signal etc are associated with unique patterns in the DNA sequence.
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Exons The coding sections of eukarotic genes, separated by introns.
Expression vector A vector which is designed to allow expression (transcription and translation) of the inserted section of DNA.
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RNA polymerase An enzyme that catalyzes the formation of RNA from NTPs, using a strand of DNA or RNA as a template. RNA splicing Removal of introns and joining of exons in a primary transcript (hnRNA).
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