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Enhancer


Enhancer
A DNA sequence element to which transcriptional factors bind. Binding of transcriptional factors increases gene transcription.
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A transgenic construction inserted in a chromosome which is used to identify tissue-specific enhancers in the genome.
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Enhancer
In genetics, an enhancer is a short region of DNA which can be bound with proteins (namely, the trans-acting factors, much like a set of transcription factors) to enhance transcription levels of genes (hence the name) in a gene-cluster.
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Enhancer
A cis-regulatory sequence that can elevate levels of transcription from an adjacent promoter. Many tissue specific enhancers can determine spatial patterns of gene expression in higher eukaryotes.
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enhancers
silencers
Adjacent genes (RNA-coding as well as protein-coding) are often separated by an insulator which helps them avoid cross-talk between each other's promoters and enhancers (and/or silencers).
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Enhancer
A cis-acting regulatory sequence that can increase transcription from an adjacent promoter.
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enhancer
A DNA sequence that recognizes certain transcription factors that can stimulate transcription of nearby genes.
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ENHANCER - A eukaryotic transcriptional control element which is a DNA sequence which acts at some distance to enhance the activity of a specific promoter sequence.
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enhancer - DNA sequence in a gene that influences the gene's expression by increasing or decreasing its rate of RNA synthesis (via effects on binding and transcription of the basal transcription apparatus including RNA Polymerase); ...
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Enhancer: An enhancer is a cis-acting nucleotide sequence to which transcription factor(s) bind, and which increases the transcription of a gene.
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Enhancer
: A
cis
-acting (on either side of a gene) enhancer of
promoter
function without any promoter activity of its own. They are located 10 to 50 kb downstream or upstream of a gene. They may be tissue-specific.
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enhancers cis-acting DNA sequences that facilitate the expression of a given gene by increasing transcription independent of the enhancer orientation or distance relative to the promoter. ent- within enthalpy (H) The heat content of a system.
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Keeping enhancers under control. Nature 376:462-463.
Cremer, T. 1985.
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Numerous studies have been performed using the relatively laborious method of site-directed mutagenesis and subsequent expression analysis, in order to deduce the identity and nature of cis-regulatory elements (enhancers and repressors) at a ...
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Proteins called transcription factors function by binding to the promoter and to another region called the enhancer. The enhancer region may be located at a distance from the gene.
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However, in some cases (but not all) the nonsense mutation also affects the activity of an exonic splicing enhancer (ref). A BRCA1 mutation is known to have this effect (ref).
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The foreign protein then has to be purified from all of the insect cells or the bacterial cells. It has to be purified and then it's delivered generally with some sort of immune enhancer to a person.
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