Upstream/
DownstreamRefers to 5' or 3' to a reference point in
RNA. In double-
stranded
DNA,
upstream/
downstream is relative to a
transcription unit: up to down is the direction of
transcription.
Other Resources ...
Full article >>>DownstreamThe region extending in the 3' direction from a
gene.
Related Terms:
Gene ...
Full article >>>Downstream A
sequence located after a particular
site relative to the direction of
transcription and
translation (i.e. located to the 3' side of a particular
site). For example, the lacZ
structural gene is located
downstream of the lac
promoter.
Full article >>>Downstream from TNF-R1 and Fas activation - at least in mammalian
cells - a balance between pro- (like BAX, BID, or BAD) and anti-apoptotic (Bcl-Xl and Bcl-2) members of the Bcl-2
family is compromised.
Full article >>>DOWNSTREAM - Identifies
sequences proceeding farther in the direction of
expression; for example, the
coding region is
downstream from the
initiation codon, toward the 3' end of an m
RNA molecule.
Full article >>>Downstream. The region extending in a 3' direction from a
gene.
dsc
DNA. See double-
stranded
complementary DNA.
Duplex
DNA. Double-
stranded
DNA.
Full article >>>Downstream: See "
Upstream/
Downstream".
E. coli: A common Gram-negative bacterium useful for
cloning experiments. Present in
human intestinal tract. Hundreds of
strains of E. coli exist. One
strain, K-12, has been completely
sequenced.
Full article >>>Downstream: See "
Upstream/
Downstream".
Duplex: A
nucleic acid molecule in which two
strands are
base paired with each other.
E ...
Full article >>>Downstream: The direction which
RNA polymerase moves during
transcription (5' to 3') and
ribosomes moves during
translation.
Full article >>>Smo acts
downstream of hh and ptc (Alcedo, 1996)
Hh mut & PKA mut had ptc
RNA; Smo mut & PKA mut had no ptc
RNA -> suggest that smo has a significant basal activity in the absence of Hh (Ohlmeyer, 1997) ...
Full article >>>New types of "
downstream" public data
bases are also being developed for information such as
gene expression patterns. Although the idea of a single, integrated database sounds appealing, this is probably not feasible.
Full article >>>Downstream. The region extending in a 3' direction from a
gene. dsc
DNA. See double-
stranded
complementary DNA. Duplex
DNA. Double-
stranded
DNA. E
Ecology. The study of the interactions of
organisms with their
environment and with each other.
Full article >>>Recall that
transcription termination often occurs at sites considerably
downstream of the sites that, after
polyadenylation, are the 3' ends of most eukaryotic m
RNAs.
Full article >>>And that's a great question and because we really don't know what SRY is doing
downstream we can't answer that question yet. Everybody wants to say it activates another
gene, but it could easily repress a
gene.
Full article >>>Water that id dammed up no longer freely flows, placing wetland
habitats
downstream from the dam at risk.
Full article >>>It is thought that this constitutes the mechanism of choice, and allows
downstream processes to establish the compact state of the
Barr body.
Full article >>>Enhancers differ from
promoters in being farther away from, and either
upstream (5') or
downstream (3') of, the
gene they influence.
Full article >>>It is known for the
downstream executioner
caspases-3 and -7 that the activation event is proteolytic
cleavage, and this had been assumed to apply to the initiator
caspases as well.
Full article >>>oxygen sag
Oxygen decline
downstream from a pollution source that introduces materials with high biological
oxygen demands.
oxy
hemoglobin Compound formed when
oxygen combines with
hemoglobin.
Full article >>>During the early 1850's the Sacramento valley was devastated by floods, fires and from cholera epidemics. Despite this, because of its position just
downstream from the Mother Lode in the Sierra Nevada, the newfound city grew, ...
Full article >>>If a
transposon inserts itself within another
gene, it can prevent the
gene from
expressing itself. Sometimes the
transposon carries a
gene which can become activated if it becomes
inserted
downstream from an active
promoter.
Full article >>>'"/>