DNA replication or
DNA synthesis is the process of copying a double-
stranded
DNA strand in a
cell, prior to
cell division. In
eukaryotes, this is during the S phase of the
cell cycle, preceding
mitosis and
meiosis.
Full article >>>DNA Replication Complex Revealed in Exquisite Detail
A team of Harvard Medical School researchers have established the 3-dimensional,
atom-by-
atom structure of T7
DNA polymerase at work.
Full article >>>DNA ReplicationBefore a
cell can divide, it must duplicate all its
DNA. In
eukaryotes, this occurs during S phase of the
cell cycle.
The Steps: ...
Full article >>>DNA replication or
DNA synthesis is the process of copying a double-
stranded
DNA strand, prior to
cell division (in
eukaryotes, during the S phase of
mitosis and
meiosis).
Full article >>>Dr. Lawrence Brody, of the National
Human Genome Research Institute's Genetic and
Molecular Biology Branch, defines
DNA replication.
illustrated:
View illustration ...
Full article >>>DNA replication involves:
Unwinding
The
DNA must be unwound and bonds between the
bases broken so that the two
strands become separated.
Full article >>>DNA replication for the
lagging strand is discontinuous and away from the
replication fork. The small fragments synthesized are called
Okazaki fragments and later stitched together by
DNA Ligase.
Related ...
Full article >>>DNA Replication-the short story
DNA Detail
The Search for
DNA-The Birth of
Molecular Biology ...
Full article >>>DNA replication: The use of existing
DNA as a
template for the synthesis of new
DNA strands.
DNA sequence: The relative
order of
base pairs in any sample of
DNA. See
base sequence analysis.
Full article >>>DNA replication involves a great many building blocks,
enzymes and a great deal of
ATP energy (remember that after the S phase of the
cell cycle cells have a G phase to regenerate energy for
cell division).
Full article >>>DNA replication: the process by which
cells replicate or synthesize their
DNA; takes place during S phase of the
cell division cycle.
domestic
breeding: a process of directed
evolution that brings about new forms that differ from ancestral stock.
Full article >>>DNA replication: The use of existing
DNA as a
template for the synthesis of new
DNA strands. In
humans and other
eukaryotes,
replication occurs in the
cell nucleus.
Full article >>>A model of
DNA replication that accounts for a circular
DNA molecule producing linear daughter double helices.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
Full article >>>Errors during
DNA replication may lead to the
duplication of a
gene, which may diverge over time. Though the two
sequences may remain the same or be only slightly altered, they are typically regarded as separate genes (i.e.
Full article >>>Related Terms:
DNA replicationThe process of making an identical copy of a section of duplex (double-
stranded)
DNA, using existing
DNA as a
template for the synthesis of new
DNA strands.
Full article >>>Proofreading
Removal of mismatched
base pairs during
DNA replication by the 3' to 5'
exonuclease activity of
DNA polymerase, followed by resynthesis.
Protease
An
enzyme that degrades
proteins to
peptides or
amino acids.
Full article >>>Errors in
DNA replication can also lead to
mutations. Certain
gene products repair damage to
chromosomes, thereby minimizing
mutations in the
cell.
Full article >>>For example, most living things have evolved elaborate molecular machinery that checks for and corrects errors during the process of
DNA replication, keeping their
mutation rate down to acceptably low levels; conversely, ...
Full article >>>85-96 10
Chromatin-remodelling factors and the maintenance of
transcriptional states through
DNA replication Sofia Aligianni and Patrick Varga-Weisz..........
Full article >>>Origin of replication (ori ) Section of
DNA sequence which is recognised by a
cell's
DNA replication proteins, allowing initiation of new
DNA synthesis.
Full article >>>short
DNA fragment found during discontinuous
DNA replicationSource: Jenkins, John B. 1990.
Human Genetics, 2nd Edition. New York: Harper & Row
What Topic Is Your
BIOLOGY Paper On?
Full article >>>Due to
polymerase slip (a.k.a.
polymerase chatter), during
DNA replication there is a slight chance these repeat
sequences may become altered; copies of the repeat unit can be created or removed.
Full article >>>A short
sequence (of
RNA or
DNA) from which
DNA replication can initiate. May be either a synthetic
DNA or
RNA or a length of
RNA synthesized in vivo by
primase.
Full article >>>DNA helicase - an
enzyme that participates in
DNA replication by unwinding the
double helix near the
replication forkDNA ligase - fills in nicks and gaps made in poly
nucleotide strands ...
Full article >>>width="400" valign="TOP"
A linking
enzyme essential for
DNA replication; catalyzes the covalent bonding of the 3' end of a new
DNA fragment to the 5' end of a growing chain.
DNA methylation ...
Full article >>>The number of Tn10
transposons in E. coli
genomes is maintained at a constant low level.
DNA replication is required for Tn10
transposition.
The
inverted repeats of IS10R contain a GATC
sequence, a target of dam
methylation.
Full article >>>polytene chromosome - large
chromosome resulting from repeated
DNA replication and alignment of homologs in the absence of
mitosis; found in
salivary glands and some other
tissues of dipteran insects.
Full article >>>Replicon. A chromosomal region containing the
DNA sequences necessary to initiate
DNA replication processes.
Repressor. A
DNA-binding
protein in
prokaryotes that blocks
gene transcription by binding to the
operator.
Full article >>>: One of the
bacterial
DNA topoisomerases
that functions during
DNA replication to reduce molecular tension caused by
supercoiling
(
supertwisting
).
DNA gyraseproduces, then seals, double-
stranded breaks.
Full article >>>nucleus -- Membrane-bound
organelle which contains the
DNA in the form of
chromosomes. It is the
site of
DNA replication, and the
site of
RNA synthesis.
Full article >>>meiosis Process of
cell division by which
egg and
sperm cells are formed, involving a diminution in the amount of
genetic material. Comprises two successive nuclear
divisions with only one round of
DNA replication, ...
Full article >>>origin The
nucleotide sequence or
site in
DNA where
DNA replication is initiated.
Full article >>>A chromosomal region containing the
DNA sequences necessary to initiate
DNA replication processes.
Repressor. A
DNA-binding
protein in
prokaryotes that blocks
gene transcription by binding to the
operator.
Restriction endonuclease (
enzyme).
Full article >>>'"/>