DNA RepairImportance
DNA in the living
cell is subject to many chemical alterations (a fact often forgotten in the excitement of being able to do
DNA sequencing on dried and/or frozen specimens [Link]).
Full article >>>DNA RepairMultiple systems for repairing damage to
DNA have evolved, probably because of the importance of the
DNA information content.
Full article >>>DNA Repair Genes
A third type of
gene associated with
cancer is the group involved in
DNA repair and maintenance of
chromosome structure.
Environmental factors, such asionizing radiation, UV light, and chemicals, can damage
DNA.
Full article >>>DNA repair genes Genes encoding
proteins that correct errors in
DNA sequencing.
DNA replication The use of existing
DNA as a
template for the synthesis of new
DNA strands. In
humans and other
eukaryotes,
replication occurs in the
cell nucleus.
Full article >>>DNA repair: Restoration of the correct
nucleotide sequence of a
DNA molecule that has acquired a
mutation or
modification. It includes proofreading by
DNA polymerase(see
helicase).
Full article >>>A
DNA repair process initiated when
DNA polymerase bypasses a damaged area.
enzymes in the rec system are used.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
Full article >>>Post-
replication repair
A
DNA repair process which occurs after
DNA replication.
Full article >>>In 2005, scientists at Purdue University discovered in
arabidopsis an alternative to previously known mechanisms of
DNA repair, which one scientist called a "parallel path of
inheritance". It was observed in
mutations of the HOTHEAD
gene.
Full article >>>Because many of the
DNA repair mechanisms of
cells work only on paired
bases,
viruses that carry single-
stranded
DNA genomes mutate more frequently than they would otherwise. As a result, such
species may adapt more rapidly to avoid
extinction.
Full article >>>Due to
DNA replication and
DNA repair mechanisms,
mutation rates of individual genes are low, but since each
organism has many genes, and a
population has many individuals, new
mutations arise in
populations all the time.
Full article >>>DNA ligase -
protein that joins (ligates)
DNA strands; used by
cells for
DNA repair, by molecular
biologists for
gene cloning.
Full article >>>The closer together the
markers are, the lower the
probability that they will be separated during
DNA repair or
replication processes (
binary fission in
prokaryotes,
mitosis or
meiosis in
eukaryotes), ...
Full article >>>This process is the molecular basis of
crossing over during
meiosis and some
DNA repair mechanisms. Another form of
recombination,
site-specific recombination, is found where
transfer, rearrangement or
insertion of specific sections of
DNA occurs e.
Full article >>>L
ligase -- an
enzyme that functions in
DNA repair.
Linkage -- the greater association in
inheritance of two or more nonallelic genes than is to be expected from
independent assortment; genes are linked because they reside on the same
chromosome.
Full article >>>'"/>