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DNA methylation


DNA methylation
A post-replication process. Cytosine residues in CpG sequences are methylated, forming gene-specific methylation patterns. Methylation of promoter regions correlates with gene expression patterns.
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DNA methylation
The addition of methyl groups (-CH3) to bases of DNA after DNA synthesis; may serve as a long-term control of gene expression.
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This is called epigenetic inheritance and may include phenomena such as DNA methylation, prions, and structural inheritance.
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In recent years, there has been rapid progress in understanding epigenetic mechanisms, which include differences in DNA methylation, as well as differences in chromatin structure involving histone modifications.
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The shut-down of the XIST locus on the active X chromosome is done by methylating XIST regulatory sequences. DNA methylation usually results in gene repression so methylation permanently blocks XIST expression and permits the continued expression of ...
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The plant's ancient art of antisense technology may take advantage of gene location to determine epigenetic DNA methylation events, which in turn would regulate gene expression.
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