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DNA damage


DNA repair refers to a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as UV...
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The DNA damage theory of aging proposes that aging is a consequence of unrepaired DNA damage accumulation. Damage in this context includes chemical reactions that mutate DNA and/or interfere with DNA replication. Although both mitochondrial and nuclear DNA damage can...
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Science and technology news stories tagged with keyword: dna damage. ... sex helps to reduce sperm DNA damage and improve fertility. Medicine & Health ...
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Evidence suggests that damage to human sperm DNA might adversely affect ... Sperm DNA damage has been associated with high levels of reactive oxygen species, ...
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Multiple lines of evidence point to DNA damage being critical component in cell death ... For therapeutic radiation, damage to DNA is caused by energy ...
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If the damage is not repaired, it may interfere with DNA replication or transcription. ... Once DNA damage is present, its removal may proceed in whole or in ...
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Apurinic/apyrimidinic (AP) sites are one of the major types of DNA lesions formed during the course of base excision and repair of oxidized, deaminated or alkylated ...
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DNA damage caused by oxygen-derived species including free radicals is the most ... evidence for the role of this type of DNA damage in the aging process. ...
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... possibly repairing the molecular and biochemical damage known as aging ... Aging damage occurs to molecules (DNA, proteins, lipids), to cells and to organs. ...
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Author: Carol Bernstein, Title: DNA Damage and Cancer, Date: 14 January 2009, Publisher: SciTopics ... The incidence of DNA damage is likely higher than this ...
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Much of the early work on radiation damage has focused on DNA because of its unique ... The kinds of damage. inflicted on DNA are summarized in Figure-1 and ...
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DNA Damage ELISA Kits. HT 8-oxo-dG ELISA Kit. Fragment Length Analysis by Repair Enzymes (FLARE ... UV Damage Enzymes. Ultraviolet DNA Endonuclease (UVDE) E. ...
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3 Sperm DNA damage: clinical significance in the era of assisted reproduction ... 6 Determination of cell fate by c-Abl activation in the response to DNA damage ...
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