Conformation

trans conformation In a heterozygote involving two mutant sites (ab) within a gene or gene cluster, the arrangement, Ab/aB. See cis conformation
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
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The mechanism is based on the prion hypothesis, which posits that self-perpetuating changes in the conformation of single protein, PrP, underlie the severe neurodegeneration associated with the transmissible spongiform enchephalopathies in mammals.
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Conformational protein folding is usually much faster (typically 10-100 ms) than cis-trans isomerization (10-100 s).
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CONFORMATIONAL EPITOPE - An epitope which is dependent upon folding of a protein; amino acid residues present in the antibody binding site are often located at sites in the primary sequence of the protein which are at some distance from each other.
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Conformation: The 3-dimensional structure of a molecule.
Conformational epitope: Also called a "global epitope". An epitope comprised of contiguous but physically discontinuous components of the immunogenic molecule.
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Beta Conformation
consists of pairs of chains lying side-by-side and
stabilized by hydrogen bonds between the carbonyl oxygen atom on one chain and the -NH group on the adjacent chain.
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Single stranded conformational polymorphism (SSCP)
A method for distinguishing between similar sized DNA fragments according to the mobility of the single-stranded DNA under polyacrylamide gel electrophoresis.
Heteroduplex analysis ...
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SSCP: single-strand conformation polymorphism
RPA: ribonuclease-protection assay
RFLP: restriction fragment length polymorphism
PCR: polymerase chain reaction amplification with mutation-specific primers ...
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Contrast with intermediary metabolism secondary structure The localized conformation of a protein. sedimentation coefficient A physical constant specifying the rate of sedimentation of a particle in a centrifugal field under specified conditions.
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Our algorithms have linear (3n) or quadratic time and achieve a three-dimensional protein conformation that has a guaranteed free energy no worse than 8 of optimal.
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Whether a carbohydrate is D or L has to do with the isomeric conformation of the hydroxyl on carbon 5. If it is to the right in the Fischer projection, then the ring form will be the D enantiomer, if it is to the left, it will be the L enantiomer.
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[Normally], when a hormone binds to a receptor, you get these really neat conformational changes that then cause gene expression to ensue. Most androgen insensitivity cases involve mutations where the hormone would be binding.
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Conditions that alter the conformation of a protein which regulates expression of other genes.
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The essence of the motor system is that myosin makes transient contact with the actin filaments and undergoes a conformational change before releasing contact.
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For proteins, a process in which a protein unravels and loses its native conformation, thereby becoming biologically inactive. For DNA, the separation of the two strands of the double helix.
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Denature the process whereby a protein looses its native conformation
(de = from down out; nata = born produced)
Dendrite the "incoming" end of a neuron
(dendro = tree) ...
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The substrate molecule normally does not fit exactly in the active site. This induces a change in the enzymes conformation (shape) to make a closer fit.
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carrier proteins - membrane transport protein that binds to a solute and transports it across the membrane by undergoing a series of conformational changes ...
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When rhodopsin (Rh) absorbs a photon of light its chromophore, 11-cis-3-hydroxyretinal, is isomerized to all-trans-3-hydroxyretinal. Rh undergoes a conformational change into its active form, metarhodopsin.
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