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Codon Bias


Codon usage bias refers to differences among organisms in the frequency of occurrence of codons in protein-coding DNA sequences (genes). A codon is a series of three nucleotides (triplets) that encodes a specific amino acid residue in a polypeptide chain.
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GenScript's codon optimization technology can increase the protein expression ... Codon bias and protein expression. Codon bias has been identified as the ...
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Codon bias. Biases in codon usage provide evidence for constraints on silent sites. ... has also been suggested that codon biases are caused by directional (or ...
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Codon bias is exploited by the biotechnology industry to improve the yield of ... The ability to manipulate codon bias may also usher in a era of safer vaccines. ...
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Codon Usage Bias (CUB, defined here as deviation from equal usage of synonymous ... The results put the concept of "codon bias" into a novel perspective. ...
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This phenomenon is known as context-dependent codon bias (CDCB) (1–3) ... CDCB has been examined to a much lesser extent than codon bias itself. ...
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Levels and Patterns of Codon Usage in Drosophila. Levels of Bias. Several measures of the degree of codon bias for a given gene have been developed. ...
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Our dinucleotide and codon bias analysis method is based on formulas published ... Mean Codon bias deviation (CDNBias dev): It is the mean deviation (MD) of all ...
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patterns of codon bias evolution on the X chromosome and autosomes in Drosophila ... Furthermore, genes that become X-linked evolve higher codon bias ...
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tion and that codon bias is maintained by a balance between selection, ... preferred codons is weak only when codon bias approaches equilibrium ...
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Synonymous codon usage bias is deter- mined by a combination of mutational biases, selec ... method for estimating levels of codon bias and de ...
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A codon bias space, where genomes are identified by their preferred codons, is ... These results suggest that codon bias space might reflect the geometry of a ...
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This causes a strong codon difference bias in the second position between ... Synonymous Codon Bias and the Divergence Rate of Genes ...
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Codon usage bias Codon usage bias refers to differences among organisms in the frequency of occurrence of codons in protein -coding DNA sequences
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This codon usage bias has been used to help identify horizontally transferred ... The relationship between codon usage bias and expressivity was first documented ...
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Codon Bias Index (CBI) (Bennetzen and Hall 1982) ... is a simple measure of overall codon bias and is analogous to the effective ...
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Thus, genes with a high codon usage bias tend to use a subset of all possible ... Codon Usage Bias Does not Correlate with Evolutionary Age ...
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Patterns and degrees of codon usage bias vary not ... Therefore, by examining codon usage bias we are able ... to estimate codon. usage bias are described in ...
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