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Caspase


Caspases, or cysteine-aspartic acid proteases, are a family of cysteine ... the apoptosome (regulated by cytochrome c and the Bcl-2 family) which activates caspase-9. ...
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An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7" ... Caspase-2 induces apoptosis by releasing proapoptotic proteins from ...
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Caspase activation can be mediated by intrinsic factors such as Bcl-2 on the ... External signals can also effect a caspase activation cascade. ...
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Using 100μl of Caspase-Glo® Reagent per assay in a 96-well format, Cat. ... The signal generated is proportional to the amount of caspase activity present. ...
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Application article describing the use of the Caspase-Glo® Assays in liver tissue. ... Both caspase-8 and -9 activities dramatically increased at 6 hours after ...
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"Role of FLASH in caspase-8-mediated activation of NF-kappaB: dominant-negative ... "The atomic-resolution structure of human caspase-8, a key activator of apoptosis. ...
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Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, ... Activation of caspase-3 requires proteolytic processing of its inactive zymogen ...
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SignalSilence<sup>®</sup> Caspase-3 siRNA Kit from Cell Signaling Technology ... Activation of caspase-3 requires proteolytic processing of its inactive zymogen ...
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As caspase family members are involved in pro-inflammatory ... I detemine if a caspase inhibitor is reversible or ... ROLE OF CASPASE-3 IN ...
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Caspase activation is a cellular event associated with the onset of apoptotic death. Detection of caspase activity provides a useful assay for analyzing one of the ...
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FLICA Caspase Detection Kits ... FLICA APOPTOSIS CASPASE DETECTION KITS FOR ... If there is an active caspase enzyme inside the cell, it will form a covalent ...
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Pan Caspase Detection Kits ... APOPTOSIS CASPASE DETECTION KITS FOR IN VITRO (FLICA) AND IN VIVO USE (FLIVO) ... Quantitate specific caspase 1, 2, 3&7, 6, 8, 9, ...
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Caspase-6, also known as Mch-2, is an intracellular cysteine protease first ... Cleavage of the caspase-6 ... caspase-6 is VEID (8), which is consistent with ...
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exact: caspase activation. Definition. Upregulation of the activity of a caspase, any of a ... GO:0043281 : regulation of caspase activity [197 gene products] ...
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Some naturally occurring caspase inhibitors have adopted classic inhibition ... This review focuses on caspase structure/function studies over the last 10 years, ...
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Caspase substrates, inhibitors, assay controls & buffers for apoptosis research. ... Caspase Substrates and Inhibitors. Apoptosis Inducers. Carbohydrates. Enzymology ...
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