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Binding site


Binding site
Specific DNA/RNA sequences a protein or protein complex bind. Some examples of protein binding sites are promoters, ribosome entry sites, and replication origins.
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binding sites Areas on the ribosome within which tRNA-amino acid complexes fit during protein synthesis.
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Binding site: A place on cellular DNA to which a protein (such as a transcription factor) can bind.
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The binding site for RNA polymerase is called the promoter. In bacteria, two features of the promoter appear to be important: ...
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Ribosome binding site
A short nucleotide sequence upstream of a gene which forms the site on the mRNA molecule where the ribosome binds. (Also called a Shine-Delgarno sequence.) ...
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Ribosome-binding site. The region of an mRNA molecule that binds the ribosome to initiate translation.
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Receptors that have binding sites for the steroid androgen. Androgen receptors are altered in people with spinobulbar muscular atrophy (SBMA).
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A region of DNA extending 150-300 bp upstream from the transcription start site that contains binding sites for RNA polymerase and a number of proteins that regulate the rate of transcription of the adjacent gene.
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We have developed a computational tool, RegSeq: Regulatory Sequence Analyzer, for high-throughput discovery of cis-regulatory elements that combines transcription factor binding site prediction (TRANSFAC) and the analysis of inter-species sequence ...
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At pH 7, the C-terminus of DnaK(387-552) mimics substrate by binding to its own substrate-binding site, as has been observed previously for truncated Hsp70 constructs.
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Promoter A short base sequence which is positioned close to the 5" end of a gene and acts as a recognition and binding site for the RNA polymerase complex prior to transcription of the gene.
RAPD Random amplification of polymorphic DNA.
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Vmax The maximum velocity of an enzymatic reaction when the binding site is saturated with substrate. vector A DNA molecule known to replicate autonomously in a host cell, to which a segment of DNA may be spliced to allow its replication.
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Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids.
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The core promoter of protein-encoding genes also contains binding sites for the basal transcription complex and RNA polymerase II, and is normally within about 50 bases upstream of the transcription initiation site.
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RecA monomers have two binding sites for DNA, one for single-stranded and one for double-stranded.
The single-stranded DNA must be bound in the interior of the recA helix because its backbone is not long enough to wrap around the fiber.
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The promoter and ribosome binding site codes in Eukaryotic DNA are likely to be different than those used by the host organism.
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The next genes in this developmental cascade, the "gap genes," possess binding sites for this transcription factor. Gap genes are so named because mutations in these genes can produce larvae with "gaps" (missing several segments).
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CONFORMATIONAL EPITOPE - An epitope which is dependent upon folding of a protein; amino acid residues present in the antibody binding site are often located at sites in the primary sequence of the protein which are at some distance from each other.
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A conserved sequence 25 to 30 base pairs upstream from the site for transcription in many but not all genes; binding site for general factors involved in initiation of transcription. In prokaryotes the analogous is called Pribnow box.
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A regulatory region a short distance upstream from the 5' end of a transcription start site that acts as the binding site for RNA polymerase. A region of DNA to which RNA polymerase binds in order to initiate transcription.
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Cell-surface receptors such as the acetylcholine receptor and the insulin receptor, are located in the plasma membrane, with their ligand-binding site exposed to the external medium.
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As the cycles continue, the number of possible primer binding sites doubles each time. Therefore in a short amount of time a negligible amount of DNA can be amplified to a workable quantity.
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