Antibody

antibody
a substance engendered in an organism by the presence of a foreign material, especially bacterial proteins; an antibody is specifically antagonistic to the antigen or substance under whose influences it was formed ...
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Antibody Search & Antibody Staining Protocols
Antibody Staining Protocol Database
Lymphomation: Immunoglobulins
Immune system - edit ...
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Antibody
An antibody is a protein used by the immune system to identify and neutralize foreign objects like bacteria and viruses. Each antibody recognizes a specific antigen unique to its target.
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Antibody that attacks the body's tissues, causing autoimmune disease.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
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Dr. Jennifer Puck, of the National Human Genome Research Institute's Genetics and Molecular Biology Branch, defines antibody.
illustrated:
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Antibody Affinity
The strength with which an antibody molecule binds an epitope (= antigenic determinant) is called its affinity.
All the interactions between the two contribute to it. These are noncovalent interactions: ...
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Antibody. An immunoglobulin protein produced by B- lymphocytes of the immune system that binds to a specific antigen molecule. (See monoclonal antibodies, polyclonal antibodies.) ...
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antibody-mediated immunity: the process by which antibodies bind to antigens and destroy the microorganisms in a highly specific manner.
anticodon: the complementary codon present on a tRNA molecule.
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Antibody-mediated (humoral immunity)
Antibody-mediated (humoral) immunity is regulated by B cells and the antibodies they produce. Cell-mediated immunity is controlled by T cells.
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Antibody
A protein complex that specifically interacts with an antigen.
Anticodon
The three bases in a tRNA that are complementary to those in the codon of the mRNA.
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Antibody a chemical produced by B-cells to "tag" foreign invaders
(anti = against opposite) ...
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antibody
[Gk. anti, against]
An antigen-binding immunoglobulin, produced by B cells, that functions as the effector in an immune response.
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antibody Immunoglobulin protein, produced by B cells (or plasma cells derived from B cells), that binds with a specific antigen.
antibody titer Measure of the amount of antibody present, usually given in units per milliliter of serum.
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Phage antibody libraries represent a relatively easy way to generate antibodies against a vast number of different ligands.
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*Cambridge Antibody Technology Ltd., The Science Park, Melbourn SG8 6JJ, U.K., Eukarion, Inc., 6F Alfred Circle, Bedford, MA 01739, U.S.A.
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MONOCLONAL ANTIBODY - An antibody with very specific and often unique binding specificity which is secreted by a biologically cloned line of plasmacytoma cells in the absence of other related antibodies with different binding specificities.
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Screening by antibody is an option if the bacteria and plasmid are designed to express proteins from the cDNA inserts (see "Expression clones").
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See Catalytic antibody. Adaptive radiation. The evolution of new species or sub- species to fill unoccupied ecological niches. Aerobe. A microorganism that grows in the presence of oxygen. See Anaerobe. Agarose gel electrophoresis.
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immunoglobulin An antibody protein generated against, and exquisitely specifically for an antigen. Composed of two heavy chains (~ kDa) and two light chains (~ kDa) which are held together by disulfide bonds.
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If you want examples, lupus, which is an auto-immune disease, has too much antibody; rheumatoid arthritis has too much cellular immunity. Why does this take place? We now know it all goes back to the CD-4 lymphocyte, which is the helper cell.
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Antibody probes may also be used in aspects of recombinant DNA work, e.g. screening an expression library. The label may be radioactive (32P), biotin or digoxygenin (DIG).
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An antibody specific to the protein of interest is added to a cell lysis. Then the antibody-protein complex is pelleted usually using protein-G sepharose which binds most antibodies.
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A technique for detecting specific proteins using an antibody. Proteins are separated by electrophoresis in an acrylamide gel (PAGE), and transferred onto a membrane. The membrane is then probed with an antibody.
Related ...
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Gold clusters of 0. 8-1. 4 nm that are often attached to an antibody or Fab fragment. The clusters are visualized in the electron microscope by using a silver- or gold-based size-enhancement procedure.
VOLUME RENDERING ...
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antigen - a molecule which reacts with preformed antibody at the specific receptors on T and B cells. Antigens are the ligands that react with the products of an immune response ...
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: The specific site on an antigen that is recognized by an antibody (also known as the antigenic determinant).
Escherichia coli ...
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The Evolution of Improved Fitness by Random Mutation plus Selection The notion that all the complexity we see before us today could have been the result of naturally selected random mutations seems mind-boggling. But antibody genes provide a clear ...
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leucocyte
A white blood cell; typically functions in immunity, such as phagocytosis or antibody production.
Covered in Lab 17 Rat and Frog Comparative Anatomy ...
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Our bodies contain millions of different antibodies, each produced by a type of white blood cell called a lymphocyte. A single lymphocyte can produce only one specific kind of antibody, thus, there are millions of different kinds of lymphocytes.
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Western blotting analysis -- a technique used to identify a specific protein; the probe is a radioactively labeled antibody raised against the protein in question.
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