Alkylating agents (e.g. N-ethyl-N-nitrosourea (ENU)) These agents can mutate both replicating and non-replicating
DNA. In contrast, a
base analog can only mutate the
DNA when the analog is incorporated in replicating the
DNA.
Full article >>>Alkylating agents (e.g. N-ethyl-N-nitrosourea (ENU))
Methylating agents (e.g. ethane methyl sulfonate (EMS))
Polycyclic hydrocarbons (e.g. benzpyrenes found in internal combustion engine exhaust)
DNA intercalating agents (e.g.
ethidium bromide) ...
Full article >>>Alkylating agents (EMS, MNNG, MNU) are used when
substitutions are desired. Small
insertions arise from the use of intercalating agents, such as acridines, ICR191, and pro
flavine, agents that slip between the
base pairs.
Full article >>>'"/>