Navigation Links
Transmembrane protein


A transmembrane protein is an integral membrane protein that spans from the internal to the external surface of the biological membrane or lipid bilayer in which it is embedded.

Extraction of a transmembrane protein in the absence of a detergent will result in aggregation and precipitation of the protein.

A hydrophobic domain of the protein resides in the oily core of the membrane, while hydrophilic domains protrude into the watery environment inside and outside the cell or compartment. Transmembrane proteins often have their N-terminal on the exoplasmic face and their C-terminal on the cytoplasmic face. Many transmembrane proteins have multiple membrane spanning alpha helix segments which anchors them to the membrane. Most transmembrane proteins have an internal topogenic sequence.

Types

There are two basic types of transmembrane proteins:

  1. Single-pass
  2. Multi-pass transmembrane proteins have multiple topogenic sequences.

Examples

See also: membrane topology, transmembrane helix, membrane protein


'"/>


(Date:9/19/2014)... unveiled today by researchers from several Harvard University ... both experienced and aspiring researchers with the intellectual ... robots made from soft, flexible materials. , With ... and other advances in manufacturing technology, soft robotics ... principles drawn from conventional rigid robot design, but ...
(Date:9/19/2014)... fairness did not evolve for the sake of fairness ... of continued cooperation, so say Frans de Waal, PhD, ... about inequity aversion (IA), which is defined as a ... in Science . , Their conclusion comes ... to address their hypothesis that it is the evolution ...
(Date:9/19/2014)... new study shows that legume plants regulate their ... molecules that are transmitted through the plant structure ... number of bacteria-holding nodules in the roots. This ... National Institute for Basic Biology, the Graduate University ... for Sustainable Resource Science in Japan. , ...
Breaking Biology News(10 mins):Soft robotics 'toolkit' features everything a robot-maker needs 2Evolution of responses to (un)fairness 2Evolution of responses to (un)fairness 3For legume plants, a new route from shoot to root 2
... published in the Nov. 20 edition of Heredity ... of the evolution of separate sexes, a theory that ... These early stages are not completely understood because the ... titillating separate-sex state too long ago for scientists to ...
... CHICAGO -- The body,s immune system hates strangers. When ... it. This is the problem when people with ... islet cells from a donor pancreas produce robust amounts ... from insulin therapy. However, the immune system tries to ...
... population, and turning research into commercial enterprises, will ... million) investment announced today by the Engineering and ... (TSB) and the Biotechnology and Biological Sciences Research ... two new centres in areas where world-class scientific ...
Cached Biology News:Two from one: Pitt research maps out evolution of genders from hermaphroditic ancestors 2Researcher tricks immune system in diabetic mice 2£20 million to fight virtual crime and treat our ageing population 2£20 million to fight virtual crime and treat our ageing population 3
Other biology definitionOther Tags