Navigation Links

The glycome is the collective identity of the entirety of carbohydrates in an organism. The glycome may in fact be one of the most complex entities in nature. The glycome is studied by glycobiology sometimes referred to as glycomics.

The genome is one of the most complex structures in an organism (although not necessarily as complex as, for example, the brains of higher organisms). The genome is responsible for the proteome, which is more complex than the genome by virtue of the fact that it combines the complexity of the genome with the complexity of the proteins which the genome specifies, proteins whose characteristics are at least partially determined by the phenomenon of molecular folding, which is one of the most complex phenomena known to science.

The glycome exceeds the complexity of the proteome as a result of the even greater diversity of the glycome's constituent carbohydrates and is further complicated by the sheer multiplicity of their possibilities of combination and interaction of the carbohydrates with each other and with proteins.

An alternative definition is the collective identity of the entirety of carbohydrates in a cell. In those definitions, the word sugar, the word glycan and the word polysaccharide can be meaningfully substituted for carbohydrate.

Ajit Varki, professor of medicine and cell and molecular biology, and director of the Glycobiology Research and Training Center at the University of California, San Diego has illustrated the scale of the glycome challenge by claiming that the glycome is:

"...probably thousands of times as complicated as the genome, in magnitude of complexity and level of diversity". (Perkel 2002)

There is a pivotal body in this field, called the Consortium for Functional Glycomics (CFG) funded by the (US) National Institute of General Medical Sciences. This body (which operates in a field called glycosciences ) includes participants in 'glycome projects' within its remit. The US Federal grant which can be said to have 'put the glycome on the political map' was described as a 'glue grant' of $34M (for the formation of the CFG, see above).

Related topics

  • Human Glycome Project
  • cellular adhesion
  • cellular communication

See also

External links and references


(Date:7/9/2014)... Rochelle, NY, July 9, 2014Biofuels derived from the oils ... to fossil fuels. To achieve this goal, optimization of ... in open pond systems, is needed. Sapphire Energy has ... of open pond algae cultivation systems, described in ... Liebert, Inc., publishers. The article is available on the ...
(Date:7/9/2014)... of Guelph scientist that involved fitting bumblebees with ... a neonicotinoid pesticide hampers bees, ability to forage ... a professor in Guelph,s School of Environmental Sciences, ... published July 9 in the British Ecological Society,s ... shows how long-term pesticide exposure affects individual bees, ...
(Date:7/9/2014)... study shows that some shark species may be able to ... come with rising temperatures. , The Arctic today is best ... wasn,t always like that. Roughly 53 to 38 million years ... Arctic was more similar to a huge temperate forest with ... ancestors of tapirs, hippo-like creatures, crocodiles and giant tortoises. Much ...
Breaking Biology News(10 mins):Controlling contamination in open algae ponds for biofuels 2Bee foraging chronically impaired by pesticide exposure: Study 2Shark teeth analysis provides detailed new look at Arctic climate change 2Shark teeth analysis provides detailed new look at Arctic climate change 3
... BUFFALO, N.Y. -- Among the many differences between girls ... and subjective -- to the list. , Results of a ... caffeine found that, in general, boys get a greater rush ... reported they felt that caffeine had a positive effect on ...
... Professor Dr. Michael Ristow,s team along with Japanese colleagues ... two independent approaches that even a low concentration of ... as well as in a model organism, the roundworm ... results in the online edition of the scientific publication ...
... is a growing concern. Protected areas are a instrument to ... of the parties in Nagoya (October 2010) set stringent new ... terrestrial and inland water and 10% of coastal and marine ... protected? Are they in the right place? Where should new ...
Cached Biology News:High-caffeine-consuming boys get greater rush from caffeine than girls 2High-caffeine-consuming boys get greater rush from caffeine than girls 3Fountain of youth from the tap 2Biodiversity in danger: Which areas should be protected? 2Biodiversity in danger: Which areas should be protected? 3
Other biology definitionOther Tags