Navigation Links

The glycome is the collective identity of the entirety of carbohydrates in an organism. The glycome may in fact be one of the most complex entities in nature. The glycome is studied by glycobiology sometimes referred to as glycomics.

The genome is one of the most complex structures in an organism (although not necessarily as complex as, for example, the brains of higher organisms). The genome is responsible for the proteome, which is more complex than the genome by virtue of the fact that it combines the complexity of the genome with the complexity of the proteins which the genome specifies, proteins whose characteristics are at least partially determined by the phenomenon of molecular folding, which is one of the most complex phenomena known to science.

The glycome exceeds the complexity of the proteome as a result of the even greater diversity of the glycome's constituent carbohydrates and is further complicated by the sheer multiplicity of their possibilities of combination and interaction of the carbohydrates with each other and with proteins.

An alternative definition is the collective identity of the entirety of carbohydrates in a cell. In those definitions, the word sugar, the word glycan and the word polysaccharide can be meaningfully substituted for carbohydrate.

Ajit Varki, professor of medicine and cell and molecular biology, and director of the Glycobiology Research and Training Center at the University of California, San Diego has illustrated the scale of the glycome challenge by claiming that the glycome is:

"...probably thousands of times as complicated as the genome, in magnitude of complexity and level of diversity". (Perkel 2002)

There is a pivotal body in this field, called the Consortium for Functional Glycomics (CFG) funded by the (US) National Institute of General Medical Sciences. This body (which operates in a field called glycosciences ) includes participants in 'glycome projects' within its remit. The US Federal grant which can be said to have 'put the glycome on the political map' was described as a 'glue grant' of $34M (for the formation of the CFG, see above).

Related topics

  • Human Glycome Project
  • cellular adhesion
  • cellular communication

See also

External links and references


(Date:10/8/2015)... , 8. Oktober 2015 Die ... tätiges Unternehmen des Bereiches Tracking, hat heute ... der Gefängnisbehörde Virginias (Department of Corrections – ... Überwachungsdienste für alle Strafen geliefert werden, die ... , Präsident für den Amerikanischen Kontinent der ...
(Date:10/7/2015)... -- --> --> According ... third quarter 2015 amounted to around 960 MSEK. This exceeds ... was communicated 20 August 2015. --> ... a continued growing demand for the company,s products, the revenues ... than during the third quarter. The revenue guidance for 2015 ...
(Date:10/6/2015)... , Oct. 6, 2015 Track Group, Inc. ... that it has signed a contract with the Virginia ... the full range of sentences under the Department,s oversight. ... the Americas. "This contract with the Virginia DOC will ... US and advances our position as a trusted leader ...
Breaking Biology News(10 mins):
... PITTSBURGH, Feb. 14, 2012 Neuro Kinetics, Inc. (NKI) ... diagnostic equipment used worldwide for neurophysiologic/ neurotologic testing, said ... of Health,s (NIH) Feedback Sessions in Washington D.C. on ... are an invitation only program funded by the NIH ...
... hearing or remembering things can complicate everyday living for ... has focused on the disease,s less frequent but more ... patients have expressed their desire for a better quality ... own central nervous system, which can cause blindness or ...
... (Feb. 9, 2012) -- A Rice University undergraduate will ... patent for his invention of an efficient way to create ... senior Manan Mehta discovered a method to create libraries of ... Jonathan Silberg. The research was reported this week in the ...
Cached Biology News:
Other biology definitionOther Tags