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New high-detail atlas offers tool to explore local environment and health

4/24/2014
Researchers have launched a detailed atlas with environment and health maps at a fine scale across England and Wales. Produced by the UK Small Area Health Statistics Unit (SAHSU), part of the MRC-PHE Centre for Environment & Health based at Imperial College London, the open-access atlas allows researchers, policy makers and members of the public to study the geographical pattern of 14 dis... [Comments]

JCI online ahead of print table of contents for April 24, 2014

4/24/2014
Ex vivo expansion of hematopoietic stem cells from cord blood Compared to hematopoietic stem cells (HSCs) isolated from adults, HSCs isolated from cord blood (CB) have enhanced proliferative potential and can lead to hematological reconstitution when engrafted in children with hematological malignancies or genetic defects. Unfortunately, small numbers of HSCs are present in single CB col... [Comments]

Kessler Foundation scientist named 63rd Mendel Lecturer by St. Peter's University

4/24/2014
West Orange, NJ. April 24, 2014. Nancy Chiaravalloti, PhD, of Kessler Foundation was named the 63rd Mendel Lecturer by Saint Peter's University in Jersey City, New Jersey. Dr. Chiaravalloti spoke on April 24, 2014 at the University's Pope Lecture Hall on the topic of "Treating Cognitive Deficits Following Neurological Illness and Injury." "It is an honor to be a part of the long lega... [Comments]

Genetic alterations in shared biological pathways as major risk factor for ASD

4/24/2014
A substantial proportion of risk for developing autism spectrum disorders (ASD), resides in genes that are part of specific, interconnected biological pathways, according to researchers from the Icahn School of Medicine at Mount Sinai, who conducted a broad study of almost 2,500 families in the United States and throughout the world. The study, titled "Convergence of Genes and Cellular Pathwa... [Comments]

Surprising new insights into the PTEN tumor suppressor gene

4/24/2014
BOSTON Ever since it was first identified more than 15 years ago, the PTEN gene has been known to play an integral role in preventing the onset and progression of numerous cancers. Consequently, when PTEN is either lost or mutated, malignant cells can grow unchecked and cancer can develop. Now a team led by investigators at Beth Israel Deaconess Medical Center (BIDMC) helps explain more p... [Comments]

Scientists find way to target cells resistant to chemo

4/24/2014
Scientists from The University of Manchester have identified a way to sensitise cancer cells to chemotherapy - making them more open to treatment. The study published today in Cell Reports , could pave the way for the development of drugs to target cells that have become resistant to treatment. The research team made the discovery whilst exploring the possible mechanisms behind resi... [Comments]

Large-scale identification and analysis of suppressive drug interactions

4/24/2014
TORONTO Baker's yeast is giving scientists a better understanding of drug interactions, which are a major cause of hospitalization and illness world-wide. When two or more medications are taken at the same time, one can suppress or enhance the effectiveness of the other. Similarly, one drug may magnify the toxicity of another. These types of interactions are a major cause of illness... [Comments]

Oxygen diminishes the heart's ability to regenerate, researchers discover

4/24/2014
DALLAS April 24, 2014 Scientific research at UT Southwestern Medical Center previously discovered that the newborn animal heart can heal itself completely, whereas the adult heart lacks this ability. New research by the same team today has revealed why the heart loses its incredible regenerative capability in adulthood, and the answer is quite simple oxygen. Yes, oxygen. It is well... [Comments]

Parents of severely ill children see benefits as caregivers, says study

4/24/2014
Benefits often coexist with the negative and stressful outcomes for parents who have a child born with or later diagnosed with a life-limiting illness, says a recent study led by a researcher at the University of Waterloo. While the challenges are numerous and life-changing and stress levels high, the vast majority of parents who participated in the Waterloo-led research reported positive... [Comments]

Study supports safety of antimicrobial peptide-coated contact lenses

4/24/2014
Philadelphia, Pa. (April 24, 2014) - Contact lenses coated with an antimicrobial peptide could help to lower the risk of contact lens-related infections, reports a study in Optometry and Vision Science , official journal of the American Academy of Optometry . The journal is published by Lippincott Williams & Wilkins , a part of Wolters Kluwer Health . Studies in animals and now huma... [Comments]

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