Thalassemia

THALASSEMIA - A genetic disease that results when there is a defect in the synthesis of one (or more) of the subunits of hemoglobin. The subunits are referred to as alpha or beta globin chains.
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Thalassemia is an inherited disorder that affects the production of normal hemoglobin (a type of protein in red blood cells that carries oxygen to the tissues in the body). Thalassemia includes a number of different forms of anemia.
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Thalassemia
Definition:
Thalassemias are hereditary disorders characterized by defective production of hemoglobin. This leads to low production, and excessive destruction, of red blood cells.
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Thalassemia
Occuring in a number of different forms, thalassemia is a type of anemia. Children with thalassemia have abnormal red blood cells that are easily destroyed.
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Thalassemia. Thalassemia is a hereditary form of anemia that is most common in people of Mediterranean origin. Splenectomy is sometimes performed if the patient's spleen has become painfully enlarged.
Precautions ...
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In thalassemia major (Cooley's anemia), which is the most serious of the hereditary anemias among people of Mediterranean, Middle Eastern, and S Chinese ancestry, the erythrocytes are abnormally shaped.
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In beta thalassemia, there is a mutation (change) in both beta globin chains leading to underproduction (or absence) of beta chains, underproduction of hemoglobin, and profound anemia.
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Cooley's Anemia (Thalassemia)
DIC (Disseminated Intravascular Coagulation)
Disseminated Intravascular Coagulation
Drug-Induced Hemolytic Anemia (Drug-Induced Immune Hemolytic Anemia)
Drug-Induced Immune Hemolytic Anemia ...
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For example, sickle cell anemia mainly affects people of African ancestry, Tay-Sachs disease is especially common among Jewish people of Eastern or Central European descent, and beta thalassemia generally strikes people with Italian, Greek, ...
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Hemoglobin disorders - In some people with inherited hemoglobin disorders, the illness is mild or does not cause any symptoms (as in thalassemia minor), so treatment is not necessary.
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Detect inherited genetic disorders of your baby during pregnancy (such as Tay-Sachs disease, hemophilia, sickle cell disease, cystic fibrosis, or thalassemia), especially if either you or the father has a family history of an inherited disorder.
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Someone in your family has had thalassemia. This is a disorder that causes abnormal red blood cells. It is most common in people from Asia and Mediterranean countries (for example, Italians and Greeks).
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Mediterranean Anemia (Thalassemia)
Medullary Carcinoma of Thyroid
Medullary Cystic Disease
Medulloblastoma (Primary Brain Tumor)
Megaloblastic Anemia ...
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Hemolytic disease of the newborn
Hereditary spherocytosis
Iron deficiency anemia
Osteopetrosis
Pernicious anemia
Sickle cell disease
Thalassemia
Myelodysplastic syndrome and a host of other bone marrow diseases.
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Other less-common forms of anaemia include pernicious anaemia (inability of the body to properly absorb vitamin B-12), sickle-cell anaemia (an inherited disorder) and thalassemia anaemia (also inherited).
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in the export of mRNAs from the nucleus to the cytoplasm, and in the control of mRNA stability. Polyadenylation is a key regulatory step in the expression of many genes. Aberrant polyadenylation has been shown to cause diseases such as thalassemia ...
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