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Primary amyloidosis


Primary amyloidosis occurs when the body's antibody-producing cells do not function properly and produce abnormal protein fibers made of antibody fragments. Some people with primary amyloidosis have a condition called multiple myeloma.
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Primary amyloidosis is usually treated with chemotherapy. The drug melphalan in pill form has for years been the key chemotherapeutic agent for primary amyloidosis.
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Those people with primary amyloidosis may be given drugs that suppress the body's immune system or that are more often used to treat cancer.
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There is no cure for most cases of primary amyloidosis. Treatment is directed at alleviating symptoms and trying to slow the progression of the disorder.
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Cardiac amyloidosis usually occurs during primary amyloidosis (called AL type amyloidosis). Primary amyloidosis usually accompanies multiple myeloma, a blood disorder in which too much of a certain type of protein is produced.
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Beckwith-Wiedemann syndrome (low blood sugar in a newborn with macroglossia and other enlarged organs)
Congenital hypothyroidism (newborn with decreased or, rarely, no thyroid hormone production)
Down's syndrome
Primary amyloidosis ...
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Amyloidosis may be either primary (with no known cause) or secondary (caused by another disease, including some types of cancer). Generally, primary amyloidosis affects the nerves, skin, tongue, joints, heart, and liver; ...
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Primary amyloidosis
Primary pulmonary hypertension
Pulmonary valve stenosis
Restrictive cardiomyopathy
Right-sided heart failure
Secondary systemic amyloidosis
Senile cardiac amyloidosis
Stroke
Tetralogy of Fallot
Transient ischemic attack (TIA) ...
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