Drug Resistance

Drug Resistance
Related Category: Pathology
condition in which infecting bacteria can resist the destructive effects of drugs such as antibiotics and sulfa drugs.
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DRUG RESISTANCE: The ability of some disease-causing microorganisms, such as bacteria, viruses, and mycoplasma, to adapt themselves, to grow, and to multiply even in the presence of drugs that usually kill them. See Cross-Resistance.
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Drug resistance The result of cells' ability to resist the effects of a specific drug. Dysphagia Difficulty in swallowing. Dyspnea Difficult or painful breathing; shortness of breath. Dysuria Difficult or painful urination.
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Why can drug resistance lead to an epidemic?
If there are forms of HIV that are resistant to drug treatment, they are more likely to survive and infect other people. Resistant forms of HIV are able to spread more easily and infect more people.
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GENOTYPIC DRUG RESISTANCE TEST
Genotypic testing can help determine whether specific gene mutations, common in people with HIV, are causing drug resistance and drug failure.
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The problem of drug resistance
The history of antimalarial medicine has been marked by a constant struggle between evolving drug-resistant parasites and the search for new drug formulations.
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PhenoSense HIV A rapid phenotypic drug resistance assay that directly measures the sensitivity or resistance of a patient's HIV to currently available antiretroviral drugs; provides drug susceptibility information in 2 weeks, ...
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Other complications include drug resistance to particular TB strains and a relapse of the disease in some patients.
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HIV Patients Not So Concerned About Drug Resistance?
HIV Treatment Resource: Black-Box Warning Added to HIV Drug
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Capella MAM, Capella LS. A light in multidrug resistance: Photodynamic treatment of multidrug-resistant tumors. Journal of Biomedical Science 2003;10:361-366.
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Drug resistance may be a factor in treatment failures, sometimes requiring a change in antibiotic therapy.
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Dunne, R. L., L. A. Dunn, P. Upcroft, et al. "Drug Resistance in the Sexually Transmitted Protozoan Trichomonas vaginalis." Cell Research 13 (August 2003): 239-249.
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This is called drug resistance. When this occurs, your doctor may give you a different antibiotic. For example, your doctor may give you oral doxycycline when oral erythromycin no longer works on your acne.
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Belongs to a family of drugs called calcium channel blockers. It is being investigated for use with anticancer drugs to prevent or overcome drug resistance and improve response to chemotherapy.
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Drug treatments, using a combination of several drugs known as highly active antiretroviral therapy, have greatly improved the outlook in AIDS. But drugs can't cure the infection and side effects and drug resistance are still a major problem.
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Antibiotic resistance: The ability of bacteria and other microorganisms to withstand an antibiotic to which they were once sensitive (and were once stalled or killed outright). Also called drug resistance.
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