Navigation Links
Hematopathology


Hematopathology is the branch of pathology which studies diseases of hematopoietic cells (see below). A hematopathologist looks at peripheral blood smears, bone marrow aspirates and biopsies, lymph nodes, and other tissues, and uses his/her expertise to diagnose diseases such as lymphomas and leukemias. The hematopathologist uses traditional microscopy to look at the specimen, but also relies on laboratory values, immunohistochemistry, flow cytometry, and molecular diagnostic tests to make the most accurate diagnosis. The hematopathologist works closely with the hematologist/oncologist specialty doctor who sees the patient and decides on the best treatment based upon the diagnosis.

Diseases of Hematopoietic Cells

The major disease of hematopoietic cells fall into several categories, which include chronic myeloproliferative disease, myelodysplastic syndromes, leukemias, lymphomas, plasma cell neoplasms, and histiocytic and mast cell neoplasms. Hematopathologists from all over the world have agreed on a standard classification system, called the "WHO classification".[1] Leukemias are mainly bone marrow and blood based and can be subclassified as chronic leukemia and acute leukemia. Chronic leukemia is the proliferation of too many mature blood cells, and is called that because it is a chronic process clinically. Examples are chronic myelogenous leukemia and chronic lymphocytic leukemia. Acute leukemia is the proliferation of too many immature blood cells, called myeloblasts, which have lost the ability to become mature cells. This is usually a very aggressive disease if untreated. Fortunately, treatment of both types of leukemia has improved greatly over the past few decades. Lymphomas are diseases that are mainly based in lymph nodes. Hematopathologists have named different lymphomas after the type of lymphocyte that has become malignant. Thus there are B cell lymphomas, T cell lymphomas, and NK cell lymphomas. The hematopathologist uses immunohistochemistry and flow cytometry, techniques using antibodies to specific lymphocyte surface markers, to determine the type of lymphoma in the pathology specimen.

Notes

  1. ^ Jaffe, ES, Harris, NL, Stein, H., and Vardiman, JW, eds. Pathology and Genetics: Tumours of Haematopoietic and Lymphoid Tissues, World Health Organization Classification of Tumors Series. Lyon: IARC Press, 2001.

External links



'"/>


(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... “The Journey: ... faced every danger possible to save lost souls in the Philippines. “The Journey: From ... Carole is a dedicated teacher of the Bible. She has taught all ages and ...
(Date:10/12/2017)... ... , ... Planet Fitness, one of the largest and fastest growing franchisors and ... flagship location in Covington, LA at 401 N. U.S. Highway 190, in January of ... Depot in the Holiday Square shopping center. Its location allows it to serve both ...
(Date:10/12/2017)... ... ... Asante, a nationally recognized health system in southern Oregon, ... health joint venture through an agreement, effective October 1, 2017, to create AccentCare ... company with Asante, delivering clinically integrated care, for the past eight years. This ...
(Date:10/12/2017)... ... October 12, 2017 , ... Leading pediatric oncology experts at Children’s ... the 49th Congress of the International Society of Paediatric Oncology (SIOP) Oct. ... Center for Cancer and Blood Disorders at Children’s National, and Stephen P. Hunger, ...
(Date:10/12/2017)... ... , ... In the United States, single-family home owners pay ... York, New Jersey, Massachusetts, Texas, Virginia, Connecticut, and California—the average is $7,000 a ... rates, which contributes to the relatively lower cost of living in places like ...
Breaking Medicine News(10 mins):
Other medicine definition