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Urea


The urea cycle, also known as the ornithine cycle, is a cycle of biochemical reactions occurring in many animal organisms that produces urea from ammonia (NH4+). This cycle was the first metabolic cycle discovered (Krebs and Hensenleit, 1932).
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Urea is much less toxic than ammonia, therefore organisms which can't easily and quickly remove ammonia usually have to convert it to some other substance, like urea or uric acid.
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Urea is the chief nitrogenous waste of mammals.
Most of our nitrogenous waste comes from the breakdown of amino acids.
This occurs by deamination.
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urea
[Gk. ouron, urine]
A soluble form of nitrogenous waste excreted by mammals and most adult amphibians.
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urea A nitrogen-containing waste product excreted in the urine of many vertebrates
uredium (pl. uredia)The structure that produces uredospores in rust fungi; sometimes called a uredinium.
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urea: a component of urine that results from amino acid breakdown in the liver.
ureters: tubes that carry waste from the kidneys to the urinary bladder for storage or release.
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Urea Molecular model and information about the inorganic synthesis of this molecule.
The Fluid Regulation System NASA article (with illustrations) about fluid regulation and how it relates to space.
Back to Table of Contents ...
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urea cycle A metabolic pathway in vertebrates, for the synthesis of urea from amino groups and carbon dioxide; occurs in mitochondrial and cytoplasmic compartments of the liver. ureotelic Organisms which excrete excess nitrogen in the form of urea.
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In 1828, Friedrich Whler published a paper about the synthesis of urea, proving that organic compounds can be created artificially, in contrast to the common belief of the time that organic compounds can only be made by living organisms.
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For protein, this usually means the inclusion of 2-ME (which reduces disulfide bonds between cysteine residues) and SDS and/or urea in an acrylamide gel.
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A method for separating DNA fragments according to their mobilities under increasingly denaturing conditions (usually increasing formamide/urea concentrations). See also TGGE, SSCP and heteroduplex analysis.
Related Terms: Deoxyribonucleic acid (DNA) ...
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The inner fluid phase has most of the enzymes of the tricarboxylic acid cycle and some of the urea cycle. The inner membrane contains the components of the electron transport chain.
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Most of these defects cause significant disability that cannot be treated satisfactorily by such other approaches as modifying the diet or supplying the enzyme. Some examples include adrenoleukodystrophy, galactosemia, and the urea cycle disorders.
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The United States has exported in food products E. coli 0157, which causes hemolytic urea and is roughly the most difficult form of enteric, or stomach, microbial disease that we've introduced into the world in quite a number of decades.
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