Transcription start site

Transcription start site
The basal promoter
An Analogy
Hormones exert many of their effects by forming transcription factors.
Embryonic development requires the coordinated production and distribution of transcription factors.
Enhancers ...
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Transcription Start Site (TSS)
Approximately -35
A binding site for RNA polymerase ...
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Transcription start site
Site within a gene where transcription of RNA begins.
Terminator ...
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Transcription start site: The point in a DNA sequence at which transcription of a gene into RNA begins.
Transcriptome: The complete set of RNAs transcribed from a genome.
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Regions of DNA rich in CpG dinucleotides, also known as CpG islands, are often found upstream of the transcription start site in both tissue specific and housekeeping genes.
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A sequence on DNA that functions as the RNA polymerase binding site, thus defining the transcription start site.
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A regulatory region a short distance upstream from the 5' end of a transcription start site that acts as the binding site for RNA polymerase. A region of DNA to which RNA polymerase binds in order to initiate transcription.
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Sequences on the 5' end of mRNA but not translated into protein. It extends from the transcription start site to just before the ATG translation initiation codon. 5' UTR may contain sequences that regulate translation efficiency or mRNA stability.
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They are ubiquitous and interact with the core promoter region surrounding the transcription start site(s) of all class II genes.
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A region of DNA extending 150-300 bp upstream from the transcription start site that contains binding sites for RNA polymerase and a number of proteins that regulate the rate of transcription of the adjacent gene.
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