Stop codon

Stop Codons
In classical genetics, the stop codons were given names: UAG was amber, UGA was opal, and UAA was ochre. These names were originally the names of the specific genes in which mutation of each of these stop codons was first detected.
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stop codon The codon on a messenger RNA molecule where protein synthesis stops.
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Stop codon. See Termination codon.
Structure-functionalism. The scientific tradition that stresses the relationship between a physical structure and its function, for example, the related disciplines of anatomy and physiology.
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STOP CODON - A codon (UAA, UAG, UGA) which terminates translation.
STREPTAVIDIN - A bacterial analog of egg white avidin.
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Stop codon: That codon at which translation of an mRNA molecule into a polypeptide is terminated. In the Universal Code this may be: UGA, UAG, or UAA.
Streptavidin: A bacterial analog of egg white avidin.
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premature STOP codons. Translation of these produces a truncated protein that is probably ineffective and may be harmful. The problem is solved by Nonsense-Mediated mRNA Decay (NMD).
no STOP codon. These produce "nonstop" transcripts.
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Opal codon
The UGA stop codon.
Opal mutation
A change in a codon to create the nonsense codon UGA (the opal codon).
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A long DNA sequence that is unin- terrupted by a stop codon and encodes part or all of a protein. (See Reading frame.) Operator.
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termination codons stop codons. termination factors Protein factors of the cytoplasm required in releasing a completed polypeptide chain from a ribosome. AKA release factors.
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In classical genetics, the stop codons were given names: UAG was amber, UGA was opal, and UAA was ocher. These names were originally the names of the specific genes in which mutation of each of these stop codons was first detected.
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So to find a gene, the program looks for a start and a stop codon?
Oh, I wish it were as easy as just finding a start and finding a stop. A start codon for a protein is "ATG." You're going to bump into a start codon ATG pretty often.
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Results in exposure of a premature stop codon, loss of an exon, or inclusion of an intron.
Mutation of a splice site reducing specificity.
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of representing candidate solutions in a robust way does not arise in nature, because the method of representation used by evolution, namely the genetic code, is inherently robust: with only a very few exceptions, such as a string of stop codons, ...
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A mutation that results in a stop codon so that incomplete proteins are produced, it is called a nonsense mutation.
A mutation that produces a functioning protein is called a silent mutation.
Exercise - Understanding DNA, mRNA, tRNA, and protein.
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Everything between the stop codon and the polyA tail is considered to be 3' untranslated (see Figure 4). The 3' untranslated region may affect the translation efficiency of the mRNA or the stability of the mRNA.
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A sequence of DNA following an initiation codon that does not contain a stop codon. Detection of an open reading frame in DNA implies the presence of a gene that codes for a protein.
Related Terms: DNA sequence ...
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The CDS begins with the start codon's first nucleotide and ends with the stop codon's third nucleotide.
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A single DNA base substitution resulting in a stop codon.
explained:
Listen to a detailed explanation.
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A mutation that changes an amino acid codon to one of the three stop codons, resulting in a shorter and usually nonfunctional protein.
noradrenaline ...
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: A DNA segment coding for a specific polypeptide, and includes its own start and stop codons. When an mRNA encodes two or more proteins, it is called
polycistronic
.
Clade ...
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Regions of DNA/RNA sequences that code for proteins. Usually starts with a start codon (ATG) and ends with a stop codon.
Related
ORF ...
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Yet, insertion of in frame stop codons did not block the ability of the fragment to complement.
Parts of the RNA sequence are complementary to the 3' flanking sequences of exon 1 and others to the 5' flanking sequences of exon 2.
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Nonsense mutation -- a mutation in which a codon is changed to a stop codon, resulting in a truncated protein product.
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