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SSCP
See single stranded conformational polymorphism
Related Terms: Single stranded conformational polymorphism (SSCP) ...
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SSCP: single-strand conformation polymorphism
RPA: ribonuclease-protection assay
RFLP: restriction fragment length polymorphism
PCR: polymerase chain reaction amplification with mutation-specific primers ...
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Methods such as single strand conformation polymorphism (SSCP) and denaturing gradient gel electrophoresis (DGGE) have yielded limited success in detecting mutations in short DNA fragments.
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Single-strand conformational polymorphism (SSCP): Relies on secondary and tertiary structural differences between denatured and rapidly cooled amplified DNA fragments that differ slightly in their DNA sequence; ...
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