Response element

Response elements are binding sites for transcription factors. Sequences of response elements are required for the functions of the transcription factors.
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Response element: By definition, a "response element" is a portion of a gene which must be present in order for that gene to respond to some hormone or other stimulus. Response elements are binding sites for transcription factors.
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The response element is part of the promoter of a gene. Binding by the receptor activates or represses, as the case may be, the gene controlled by that promoter.
It is through this mechanism that steroid hormones turn genes on (or off).
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cAMP response element binding protein-1 (CREB-1) is thought to be the primary transcription factor in the cascade of gene expression that leads to prolonged structural changes to the synapse enhancing its strength[23].
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In a variety of organisms, including flies (Drosophila) and humans, one enzyme, CREB (cyclic-AMP response element binding protein), seems to be involved in the steps that facilitate this new protein expression.
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