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Pribnow box


Pribnow box
Relatively invariant sequence of six nucleotides (consensus TATAAT) in prokaryotic promoters centred at the position minus 10 (10 base pairs upstream from the transcription start site). In eukaryotes the analogous is called TATA box.
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The sequence at -10 is called the Pribnow box and usually consists of the six nucleotides TATAAT. The Pribnow box is absolutely essential to start transcription in prokaryotes. The other sequence at -35 usually consists of the six nucleotides TTGACA.
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