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Nuclein


Discovery of the mutant alpha synuclein genes raises genetic-testing issues similar to those for such other late-onset diseases as Alzheimer's disease and Huntington's disease.
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This material, designated nuclein by Miescher, consists of proteinaceous material and a substance rich in phosphorus.
In the 1870's, Miescher isolated a similar substance from salmon sperm.
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Friedrich Miescher (1844-1895) discovered a substance he called "nuclein" in 1869. Somewhat later, he isolated a pure sample of the material now known as DNA from the sperm of salmon, and in 1889 his pupil, Richard Altmann , named it "nucleic acid".
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Since it came from nuclei, Meischer named this new chemical, nuclein. Subsequently the name was changed to nucleic acid and lastly to deoxyribonucleic acid (DNA). Robert Feulgen, in 1914, discovered that fuchsin dye stained DNA.
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Nucleic acids were discovered in 1869 by Johann Friedrich Miescher (1844-1895), who called the material 'nuclein' since it was found in the nucleus.
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His experiments revealed that nuclei contained a chemical that contained nitrogen and phosphorus but no sulfur. He called the chemical nuclein because it came from nuclei. It later became known as nucleic acid.
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Nuclein. The term used by Friedrich Miescher to describe the nuclear material he discovered in 1869, which today is known as DNA. Nucleoside. A building block of DNA and RNA, consisting of a nitrogenous base linked to a five carbon sugar.
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