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Neurospora crassa


Neurospora crassa and the
One Gene - One Enzyme Theory
Neurospora crassa is an ascomycete, the red bread mold. Like all fungi, it reproduces by spores.
It produces two kinds of spores: ...
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Neurospora crassa is a type of red bread mold of the phylum Ascomycota. The genus name, meaning "nerve spore" refers to the characteristic striations on the spores that resemble axons.
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Neurospora crassa, a filamentous fungus, contains little repetitive DNA other than rDNA repeats. It grows as a scyntium with haploid nuclei. A very brief diploid phase occurs.
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They used Neurospora crassa as an experimental organism. It had a short life-cycle and was easily grown. Since it is haploid for much of its life cycle, mutations would be immediately expressed. The meiotic products could be easily inspected.
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Beadle and Tatum's key experiments involved exposing the bread mold Neurospora crassa to x-rays, causing mutations. In a series of experiments, they showed that these mutations caused changes in specific enzymes involved in metabolic pathways.
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