Mutation

mutation rate
the rate at which mutations occur at a specific locus; usually expressed as mutations per gamete per locus per generation
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
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Mutations are considered the driving force of evolution, where less favorable (or deleterious) mutations are removed from the gene pool by natural selection, while more favorable (beneficial or advantageous) ones tend to accumulate.
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Mutation = Damage - Repair
Mutations are stably inherited changes in the nucleotide sequence of the genome.
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Mutations
In the living cell, DNA undergoes frequent chemical change, especially when it is being replicated (in S phase of the eukaryotic cell cycle). Most of these changes are quickly repaired. Those that are not result in a mutation.
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Definition of mutation :
1) The process producing a gene or a chromosome differing from the wild-type.
2) The gene or chromosome that results from such a process.
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The study of the components of a biological system through a study of mutations affecting that system.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
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Mutations are permanent, sometimes transmissible (if the change is to a germ cell) changes to the genetic material (usually DNA or RNA) of a cell.
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Mutations happen.
They happen with great regularity.
Almost all mutations are neutral.
Of the remainder, benefit/harm depends on circumstances ...
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Chapter 11
Mutations of the mitochondrial genome:clinical overview and possible pathophysiology of cell damage
Steven M.Rothman ...
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Mutations are changes in the DNA.
Frameshift
A frameshift mutation is usually severe, producing a completely nonfunctional protein.
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A permanent structural alteration in DNA. In most cases, DNA changes either have no effect or cause harm, but occasionally a mutation can improve an organism's chance of surviving and passing the beneficial change on to its descendants.
explained: ...
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Mutation Lists Vital
Complete and current mutation lists are vital for studying genotype-phenotype relationships, treating patients with similar phenotypes, and analyzing amino-acid residues important in the function of gene products.
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Mutation of DNA polymerase that increases the overall mutation rate.
Related Terms: Mutation ...
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Mutations in p53 are almost all cell specific-occasionally they are inherited. But mostly they are mutations that either abrogate the function of p53 entirely or alter its function.
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mutation: a random change in the gene pool of a population that gives rise to new alleles and is the source of variation in a population.
mutualism: a living arrangement in which both partners benefit.
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Mutation: A spontaneous or induced change in the DNA of a cell.
Nucleotide: A molecular subunit of DNA or RNA consisti ng of a base (adenine, guanine, thymine, or cytosine in DNA; adenine, guanine, uracil, or cytosine in RNA).
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Mutation
Any heritable alteration in the base sequence of the genetic material. See Types of mutations ...
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mutation - a change in the DNA sequence that constitutes a genetic mistake.
oligosaccharides. Polysaccharides are molecules with thousands of monosaccharideunits.
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Mutations and evolution
Just as there are many factors influencing the expression of a particular DNA strand, there are many ways to have genetic mutations.
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mutation
(myoo-tay-shun) [L. mutare, to change]
A rare change in the DNA of genes that ultimately creates genetic diversity.
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mutation Any heritable change in the nucleotide sequence of DNA; can involve substitutions, insertions, or deletions of one or more nucleotides.
mutation rate The average occurrence of mutations in a species per a given unit of time.
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mutation. The abrupt appearance of a new, heritable characteristic as the result of a change in the genetic material of one individual cell.
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Mutation. An alteration in DNA structure or sequence of a gene. (See Point mutation.)
Mutualism. See Symbiosis.
Mycorrhizae. Fungi that form symbiotic relationships with roots of more developed plants.
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mutation pressure The constant resupplying of mutations to a gene pool due to a base mutation rate.
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mutations may act as dominant-negative (see also
haploinsufficiency
).
Dosage compensation ...
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Mutation a change in a gene
(muta = change)
MyocardialInfarction death of a portion of the heart muscle due to lack of blood supply due to a blocked artery
(myo = muscle; cardio = heart; infarct = filled in stuffed) ...
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Mutation: A permanent, heritable change of the genetic material, either in a single gene or in the numbers or structures of the chromosomes. Mutations do not always have harmful effects. Compare polymorphism.
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back-mutation A mutation that causes a mutant gene to revert back to its wild-type genotype. bacteriophage (phage) A virus capable of replicating in a bacterial cell.
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BACK MUTATION - Reverse the effect of a point or frame-shift mutation that had altered a gene; thus it restores the wild-type phenotype (see REVERTANT).
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insertion
A mutation involving the addition of one or more nucleotide pairs to a gene.
insertion
The more movable attachment point of a muscle.
Covered in Lab 15 Rat Muscular and Digestive Systems ...
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Usually refers to diseases that are inherited in a Mendelian fashion, although noninherited forms of cancer also result from DNA mutation. Genetic drift. Random variation in gene frequency from one generation to another. Genetic engineering.
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Allele -- an alternative form of a gene; any one of several mutational forms of a gene. Alpha-fetoprotein (AFP) -- a protein excreted by the fetus into the amniotic fluid and from there into the mother's bloodstream through the placenta.
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Auxotrophic mutant A bacterial strain which has a mutation in at least one of the enzymes in a biochemical pathway responsible for synthesising an essential substance, for example an amino acid.
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Pseudogene
A gene copy created by a gene duplication event that is no longer functional due to a disabling mutation.
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