Mutagen

mutagen
any substance that induces mutations
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
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Mutagens in fiction
Exposure to a mutagen is the means by which the anthropomorphic animals in Teenage Mutant Ninja Turtles, for example, gained their forms.
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Mutagen
In biology, a mutagen (Latin, literally origin of change) is an agent that changes the genetic information (usually DNA) of an organism and thus increases the number of mutations above the natural background level.
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The production of either random or specific mutations in a piece of cloned DNA. Typically, the DNA will then be reintroduced into a cell or an organism to assess the results of the mutagenesis.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
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Mutagenicity The capacity of a chemical or physical agent to cause permanent genetic alterations.
See also: somatic cell genetic mutation
Mutation Any heritable change in DNA sequence.
See also: polymorphism
Updated 26-Jul-05 ...
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Mutagen
A chemical or physical agent that increases the frequency of mutation, usually by directly damaging the DNA.
Mutagenesis
The formation of mutations.
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mutagen
(myoot-uh-jen) [L. mutare, to change + genus, source or origin]
A chemical or physical agent that interacts with DNA and causes a mutation.
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Mutagen. Any agent or process that can cause mutations. See Mutation.
Mutation. An alteration in DNA structure or sequence of a gene. (See Point mutation.)
Mutualism. See Symbiosis.
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mutagen Any substance capable of causing a mutation.
mutagens Agents, such as chemicals or radiation, that damage or alter genetic material (DNA) in cells.
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Mutagen: An agent capable of causing mutations. Common examples are ultraviolet light, such as in sunlight, and anthracene, a material formed during the cooking of fatty meats on a barbecue grill.
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Directed mutagenesis
Two new papers examining the phenomena of directed mutations have recently appeared in the literature. I'll quickly review these experiments in the next post.
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an active mutagen in the Ames test;
causes an increase in the incidence of tumors in rats (that are forced to swallow water containing levels of MX far higher than those ever found in water supplies).
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Saturation mutagenesis can also be carried out in vitro (kit).
Transposons can also be used in genome sequencing projects.
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While these mutagenic chemicals resided in his bladder, they attacked genes of cells lining the walls of the bladder. They attacked those genes randomly and willy-nilly creating mutations here, there and everywhere.
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SITE-DIRECTED MUTAGENESIS - The introduction of a mutation, usually a point mutation or an insertion, into a particular location in a cloned DNA fragment.
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(See Probe.) Mutagen. Any agent or process that can cause mutations. See Mutation. Mutation. An alteration in DNA structure or sequence of a gene. (See Point mutation.) Mutualism. See Symbiosis. Mycorrhizae.
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reaction insertion mutation A mutation caused by insertion of one or more extra bases between bases in DNA, or a mutagen which itself is inserted between bases (like ethidium bromide).
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Pauling first described the a-helix nearly 50 years ago, yet new features of its structure continue to be discovered, using peptide model systems, sitedirected mutagenesis, advances in theory, ...
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Filamentous bacteriophages are used to produce single-stranded DNA for sequencing or in vitro mutagenesis (eg. M13), and as vectors for Phage display expression screening systems ...
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Since mutations can be induced (by radiation or chemicals), Morgan and his coworkers were able to cause new alleles to form by subjecting fruit flies to mutagens (agents of mutation, or mutation generators).
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carcinogens - a substance that causes the initiation of tumor formation. Frequently a mutagen
connective tissues B a primary tissue; form and function vary extensively. Functions include support, storage, and protection.
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DNA that has been created artificially. Basic recombinant DNA techniques include restriction digestion, ligation, site-directed mutagenesis, PCR, and cloning in plasmid or other vectors.
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