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MSH2


Recognition of a mismatch requires several different proteins including one encoded by MSH2.
Cutting the mismatch out also requires several proteins, including one encoded by MLH1.
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In vivo, the presence of mismatch recognizing proteins related to mismatch repair enzymes could block branch migration (ref). In vitro, the S. cerevisiae mismatch repair protein MSH2 specifically binds to Holliday junctions (ref).
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