Mosaicism

Mosaicism
Condition in which an individual harbors 2 or more genetically distinct cell lines; results from a genetic change after formation of a zygote, ie postzygotic event. Cf. germ line mosaicism.
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Mosaicism
The individual is a mosaic of normal chromosomal arrangements and trisomy 21 (46,XX/47,XX,+21).
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Germinal mosaicism
: A mixture of gonadal cells with different numbers of chromosome numbers or other chromosomal abnormalities. It can lead to
aneuploid
offspring from phenotypically normal parents with an unpredictable recurrence risk.
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Example of Mosaicism: Calico Cats
A calico cat has patches of orange and patches of black
X = orange ...
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Down syndrome -- a type of mental deficiency due to trisomy (three copies) of autosome 21, a translocation of 21 or mosaicism.
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This causes a pattern of gene expression called mosaicism, which occurs when different alleles of X-linked genes are expressed in different cells.
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The underlying cause is frequently sex chromosome mosaicism, such that some cells are chromosomal females while others are chromosomal males. Mosaic individuals having simultaneous aspects of both the male and the female phenotype.
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correlations in regard to cardiovascular malformations in Turner Syndrome simply because the number of individuals with the less common karyotype groups that has been studied is too small. Other studies also suggest the presence of hidden mosaicisms ...
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