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Modification


These modifications (rev) do not alter the coding capacity of those RNAs that are mRNAs. Code-altering changes are known.
Conversion of U to Y also is mediated by snoRNAs in eukaryotes. These are characterized by a conserved box H and an ACA 3' tail.
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Genetic modification or genetic manipulation are claimed to be neutral and possibly more technically correct terms for what is claimed, controversially, to be genetic engineering.
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Chapter 3
The role of post-translational modification in b-amyloid precursor protein processing
Niki Georgopoulou, Mark McLaughlin, Ian McFarlane and Kieran C.Breen1 ...
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Changes in eukaryotic mRNA, tRNA or other RNAs made after transcription has been completed. The changes to mRNA include addition of a 5'cap and 3' polyA tail and removal of introns, and to tRNA include modification of bases and removal of introns.
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Modification of DNA;
Transcription;
Translation;
Post-transcriptional modification;
RNA transport;
mRNA degradation;
Post-translational modifications; ...
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Modifications for Other Vectors
Improvements to the original optical mapping method now allow analysis of a wide range of such cloning vectors as cosmid, bacteriophage, P1, ...
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Modification (of DNA)
The specific addition of secondary residues (methyl, hydroxymethyl, glucosyl) to deoxyribonucleotides by an organism to differentiate its own DNA from other DNA or for regulatory purposes.
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Modification of RNA before it leaves the nucleus, a process unique to eukaryotes.
RNA splicing
The removal of noncoding portions (introns) of the RNA molecule after initial synthesis.
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Modification of DNA
Gene Amplification
In Drosophila (fruit flies), the chorion (eggshell) gene is copied many times in certain cells of the oviduct. These cells make large quantities of the protein needed to surround the egg.
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A modification of this procedure - called 2D gel electrophoresis - separates proteins into two dimensions, using two different characteristics.
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Gene modification. The chemical repair of a gene's defective DNA sequence. See DNA.
Gene pool. The totality of all alleles of all genes of all individuals in a particular population.
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Histone Modifications
Although their amino acid sequence (primary structure) is unvarying, individual histone molecules do vary in structure as a result of chemical modifications that occur later to individual amino acids.
These include adding: ...
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sensilla Modifications of the exoskeleton of an arthropod that, along with nerve cells, form sensory receptors.
sensillum, A small sense organ, especially in the arthropods.
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Artificial modification of a gene in a specific and directed fashion. Typically refers to substituting one DNA sequence for another to inactivate a gene or introduce or correct a mutation in a gene.
Related Terms: Gene ...
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Descent with modification: a "useful" characteristic
A useful characteristic upon which to base a definition of life is that of descent with modification: the ability of a life form to produce offspring that are like its parent or parents, ...
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Primates have modifications to their ulna and radius (bones of the lower arm) allowing them to turn their hand without needing to turn their elbow. Many primates can also swivel or turn their arms at the shoulder.
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POST-TRANSLATIONAL MODIFICATION - Modifications made to a polypeptide molecule after its initial synthesis, this includes proteolytic cleavages, phosphorylation, glycosylation, carboxylation, addition of fatty acid moieties, etc.
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Gene modification. The chemical repair of a gene's defective DNA sequence. See DNA. Gene pool. The totality of all alleles of all genes of all individuals in a particular population. Gene splicing.
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regulatory enzyme An enzyme which can be regulated by allosteric mechanisms or by covalent modification. regulatory gene A gene that gives rise to a product involved in the regulation of the expression of another gene.
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One modification that may have been a key to their success was the evolution of an upright stance. Amphibians and reptiles have a splayed stance and walk with an undulating pattern because their limbs are modified from fins.
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Epigenetics refers to modifications in gene expression that are controlled by heritable but potentially reversible changes in DNA methylation and/or chromatin structure.
Related
Chromatin DNA methylation ...
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: This term refers both to the modification of genetic risk factors by environmental risk and protective factors and to the role of specific genetic risk factors in determining individual differences in vulnerability to environmental risk factors.
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evolution -- Darwin's definition: descent with modification. The term has been variously used and abused since Darwin to include everything from the origin of man to the origin of life.
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zona reaction - in mammals, modification of the zona pellucida that blocks polyspermy; enzymes released by cortical granules digest sperm receptor proteins ZP2 and ZP3 so that they can no longer bind sperm.
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strategy that focuses on long-term prevention or suppression of pest problems through a combination of techniques such as encouraging biological control, use of resistant varieties, and adoption of alternate cultural practices such as modification of ...
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Imprinting -- a chemical modification of a gene allele which can be used to identify maternal or paternal origin of chromosome.
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Base: In molecular biology, this term refers to the purine bases adenine and guanine, and the pyrimidine bases uracil, thymine, and cytosine, or modification of these bases.
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Since the cloned DNA may have been extensively modified (for example, protein binding sites on the promoter may have been altered or removed), this procedure is often used to test whether a particular modification affects the function of a gene.
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