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Mitotic spindle


The mitotic spindle is a structure of the eukaryotic cytoskeleton involved in mitosis and meiosis, often referred to as the meiotic spindle during meiosis.
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Mitotic spindle
The mitotic spindle is a structure of the eukaryotic cytoskeleton involved in mitosis and meiosis.
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mitotic spindle A network of microtubules formed during prophase. Some microtubules attach to the centromeres of the chromosomes and help draw the chromosomes apart during anaphase. PICTURE
mole Avogadro's number (6.02 X 1023 atoms) of a substance.
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mitotic spindle apparatus - microtubule-based structure present during mitosis to which chromosomes attach and are separated toward opposite poles of the dividing cell.
morphogenesis - creation of form or structure during development.
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The mitotic spindle forms. This is an array of spindle fibers, each containing ~20 microtubules. Microtubules are synthesized from tubulin monomers in the cytoplasm and grow out from each centrosome.
The chromosomes become shorter and more compact.
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A specialized region on the centromere that links each sister chromatid to the mitotic spindle.
kingdom
A taxonomic category, the second broadest after domain.
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Eucaryote
An organism with a nuclear membrane and membrane bound organelles (e.g. mitochondria), and a mitotic spindle. This group of organisms is more correctly called Eucarya.
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anaphase The stage in mitosis and meiosis, following metaphase, in which the centromeres divide and the chromatids, lined up on the mitotic spindle, begin to move apart toward the poles of the spindle to form the daughter chromosomes.
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Since VPARP is also localized to the mitotic spindle, we examined microtubule and spindle architecture, chromosome stability and chromosome segregation in VPARP deficient mice. These data will also be presented.
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is generally flanked by repetitive DNA sequences and it is late to replicate. The centromere is an A-T region of about 130 bp. It binds several proteins with high affinity to form the
kinetochore
which is the anchor for the mitotic spindle.
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