Mismatch repair

For instance, a mismatch repair enzyme would recognize when Cytosine (C) is mistakenly paired with Thymine (T). The enzyme would then replace Thymine with Guanine (G), resulting in a correct pair between Cytosine (C) and Guanine (G).
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Mismatch repair
A mechanism that corrects mismatched base pairs that have escaped correction by the proofreading activities of the DNA polymerases.
Mispairing
Improper alignment of two nucleic acid strands.
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Mismatch Repair (MMR)
Mismatch repair deals with correcting mismatches of the normal bases; that is, failures to maintain normal Watson-Crick base pairing (A•T, C•G) ...
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Mismatch Repair
After DNA is replicated, some enzymes function to locate mismatched base pairs, remove a short segment of nucleotides containing the error, and replace the segment with the correct nucleotides.
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We have imaged the specific binding of mismatch repair enzymes to heteroduplexes between wildtype and plasmids with point mutations.
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In vivo, the presence of mismatch recognizing proteins related to mismatch repair enzymes could block branch migration (ref). In vitro, the S. cerevisiae mismatch repair protein MSH2 specifically binds to Holliday junctions (ref).
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