Marker

element ( locus, allele, DNA sequence or chromosome feature) which can be readily detected by phenotype, cytological or molecular techniques, and used to follow a chromosome or chromosomal segment during genetic analysis. See centromere marker; ...
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genetic marker
a single gene trait used to follow the transmission of chromosomes or other traits in a mating
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
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Also known as a genetic marker, a segment of DNA with an identifiable physical location on a chromosome whose inheritance can be followed. A marker can be a gene, or it can be some section of DNA with no known function.
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Markers must be polymorphic to be useful in mapping; that is, alternative forms must exist among individuals so that they are detectable among different members in family studies.
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Marker genes, such as genes for antibiotic resistance, are often engineered into plasmids. These marker genes enable researchers to know which bacteria have the plasmids. The antibiotic is added to the media used to grow the bacteria.
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Marker
An identifiable physical location on a chromosome (e.g., restriction enzyme cutting site, gene, minisatellite, microsatellite) whose inheritance can be monitored.
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Marker rescue
Repair of a mutational defect by recombination. For example, when a cell is co-infected with a mutant phage that is unable to replicate and a wild-type phage, ...
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Marker genes can be used to determine if the gene has been taken up.
Marker genes must have some distinguishable characteristic.
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Marker: An identifiable physical location on a chromosome (e.g., restriction enzyme cutting site, gene) whose inheritance can be monitored.
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Marker: Two typical usages:
1] Molecular weight size marker: a piece of DNA of known size, or a mixture of pieces with known size, used on electrophoresis gels to determine the size of unknown DNA's by comparison.
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Genetic marker. A gene or group of genes used to "mark" or track the action of microbes.
Genome. The genetic complement contained in the chromosomes of a given organism, usually the haploid chromosome state.
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Linkage of genetic markers during conjugal transfer in bacteria can be used to construct genetic maps.
Facts ...
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Each player acts as marker for one other player in the group, that is, he or she records the score on a score card. In stroke play (see below), the score consists of the number of strokes played plus any penalty strokes incurred.
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(See Selectable marker.) Bacillus. A rod-shaped bacterium. Bacillus thuringiensis (Bt). A bacterium that kills insects; a major component of the microbial pesticide industry. Backcross. Crossing an organism with one of its parent organisms.
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Linkage -- analysis of pedigree the tracking of a gene through a family by following the inheritance of a (closely associated) gene or trait and a DNA marker.
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Selectable marker A gene which is usually constitutively expressed and allows the selection of cells which carry it through growth on a selective medium.
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Microsatellites have proved to be versatile molecular markers, particularly for population analysis, but they are not without limitations.
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genetic map A diagram showing the position of specific genes along a chromosome relative to markers. genome The complete set of genetic information of an organism (is a virus an organism?).
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In most NFT-bearing neurons, we observed a strong reduction in acetylated a-tubulin immunoreactivity (a marker of stable microtubules) and a reduction of the in situ hybridization signal for tubulin mRNA.
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Gusella and his research team, who used RFLPs to identify a marker. Testing a large library of human DNA fragments, Gusella et al. found the needle in the haystack. The enzyme used was Hind III.
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Case 2: Screening for a RFLP "marker"
If a particular RFLP is usually associated with a particular genetic disease, then the presence or absence of that RFLP can be used to counsel people about their risk of developing or transmitting the disease.
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Isozymes and allozymes as molecular markers
Population genetics is essentially a study of the causes and effects of genetic variation within and between populations, ...
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Other genetic markers allowed him to identify hybrids. The two varieties were planted in a common field. Any plant's nearest neighbors were always plants of the other strain.
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Chromosome walking is a technique to clone a gene (e.g., a disease gene) from its known closest markers. The closest linked marker (e.g., EST or a known gene) to the gene is used to probe a genomic library.
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A genetic map based on the frequencies of recombination between markers during crossing over of homologous chromosomes. The greater the frequency of recombination between two genetic markers, the farther apart they are assumed to be.
lipid ...
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A set of closely linked genetic markers present on one chromosome which tend to be inherited together (not easily separable by recombination). Some haplotypes may be in linkage disequilibrium.
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The unfortunate use of ‘carrier' to describe
individuals
positive for a genetic marker is wrong, and the use of ‘carrier frequency' in that context should be replaced by ‘marker frequency'.
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gene linkage map: a map that pinpoints the location of genes based on their connection to certain marker gene sequences.
gene pool: the collection of genes within a population; as changes in the gene pool occur, a population evolves.
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The detection of identified proteins by electron microscopy, which makes use of specific antibodies that are tagged with a marker, usually colloidal gold, for visualization in the electron microscope.
LASER-SCANNING MICROSCOPY ...
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acetylcholinesterase (AChE) - an enzyme that catalyzes hydrolysis of the neurotransmitter acetylcholine into acetate and choline. Expression of AChE can serve as a marker of skeletal muscle differentiation.
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